Results 41 to 50 of about 306,199 (304)
Asymptotic stability of a Korteweg–de Vries equation with a two-dimensional center manifold
Local asymptotic stability analysis is conducted for an initial-boundary-value problem of a Korteweg–de Vries equation posed on a finite interval [0,2π7/3]{[0,2\pi\sqrt{7/3}]}.
Tang Shuxia +3 more
doaj +1 more source
Asymptotic Integration of Certain Differential Equations in Banach Space
We investigate the problem of constructing the asymptotics for weak solutions of certain class of linear differential equations in the Banach space as the independent variable tends to infinity.
Pavel N. Nesterov
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
On 3-manifolds that support partially hyperbolic diffeomorphisms
Let M be a closed 3-manifold that supports a partially hyperbolic diffeomorphism f. If $\pi_1(M)$ is nilpotent, the induced action of f on $H_1(M, R)$ is partially hyperbolic.
Parwani, Kamlesh
core +1 more source
In this paper, we investigate the nonlinear dynamic behavior of a cart–double pendulum system with single time delay feedback control. Based on the center manifold theorem and stochastic averaging method, a reduced-order dynamic model of the system is ...
Ruichen Qi +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
We investigate multiple limit cycles bifurcation and center-focus problem of the degenerate equilibrium for a three-dimensional system. By applying the method of symbolic computation, we obtain the first four quasi-Lyapunov constants.
Shugang Song +2 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Accurate Noise Projection for Reduced Stochastic Epidemic Models
We consider a stochastic Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model. Through the use of a normal form coordinate transform, we are able to analytically derive the stochastic center manifold along with the associated, reduced set ...
Anderson R. M. +6 more
core +2 more sources

