Results 101 to 110 of about 3,701,025 (306)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A novel method for determining the resistivity of compressed superconducting materials

Matter and Radiation at Extremes
The measurement of resistivity in a compressed material within a diamond anvil cell presents significant challenges. The high-pressure experimental setup makes it difficult to directly measure the size changes induced by pressure in the three ...
Liling Sun, Qi Wu, Shu Cai, Yang Ding, Ho-kwang Mao   +4 more
doaj   +1 more source

Optimization of slender wings for center-of-pressure shift due to change in Mach number [PDF]

It is observed that the center of pressure on a wing shifts as the Mach number is changed. Such shifts are in general undesirable and are sometimes compensated for by actively shifting the center of gravity of the aircraft or by using active stability ...
Andersen, Carl M.
core   +1 more source

Multiple high-pressure phase transitions in BiFeO3

, 2011
We investigate the high-pressure phase transitions in BiFeO3 by single crystal and powder x-ray diffraction, as well as single crystal Raman spectroscopy. Six phase transitions are reported in the 0-60 GPa range.
Bouvier, Pierre, Chen, Grace S., Dkhil, Brahim, Garbarino, Gaston, Guennou, Mael, Haumont, Raphaël, Kreisel, Jens   +6 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Bipedal robot center of pressure feedback simulation for center of mass learning

IAES International Journal of Robotics and Automation (IJRA)
This research aims to create a walking bipedal robot with center of pressure feedback simulation for the center of mass learning, describe its feasibility for learning, describe students' motivation to learn, and describe students' science literacy after using it.
Afrizal Mayub, Fahmizal Fahmizal, Lazfihma Lazfihma   +2 more
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Exciton engineering of 2D Ruddlesden–Popper perovskites by synergistically tuning the intra and interlayer structures

Nature Communications
Designing two-dimensional halide perovskites for high-performance optoelectronic applications requires deep understanding of the structure-property relationship that governs their excitonic behaviors. However, a design framework that considers both intra
Songhao Guo, Willa Mihalyi-Koch, Yuhong Mao, Xinyu Li, Kejun Bu, Huilong Hong, Matthew P. Hautzinger, Hui Luo, Dong Wang, Jiazhen Gu, Yifan Zhang, Dongzhou Zhang, Qingyang Hu, Yang Ding, Wenge Yang, Yongping Fu, Song Jin, Xujie Lü   +17 more
doaj   +1 more source

Mechanisms underlying center of pressure displacements in obese subjects during quiet stance

Journal of NeuroEngineering and Rehabilitation, 2011
Objective the aim of this study was to assess whether reduced balance capacity in obese subjects is secondary to altered sensory information. Design cross sectional study.
Priano Lorenzo, Vismara Luca, Bigoni Matteo, Tacchini Elena, Menegoni Francesco, Galli Manuela, Capodaglio Paolo   +6 more
doaj   +1 more source

The effect of staggering a biplane [PDF]

This investigation was carried out by request of the United States Air Service at the Massachusetts Institute of Technology wind tunnel in 1918. As the data collected may be of general interest, they are published here by the National Advisory Committee ...
Norton, F H
core   +1 more source