Results 61 to 70 of about 1,420,018 (311)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Two-way tuning of structural order in metallic glasses

Nature Communications, 2020
While metallic glasses are expected to have tunable structures, these have rarely been demonstrated. Here, the authors combine temperature and pressure to show a two-way structural tuning in rare earth-based metallic glasses beyond the nearest-neighbor ...
Hongbo Lou, Zhidan Zeng, Fei Zhang, Songyi Chen, Peng Luo, Xiehang Chen, Yang Ren, Vitali B. Prakapenka, Clemens Prescher, Xiaobing Zuo, Tao Li, Jianguo Wen, Wei-Hua Wang, Hongwei Sheng, Qiaoshi Zeng   +14 more
doaj   +1 more source

On the theory of translationally invariant magnetohydrodynamic equilibria with anisotropic pressure and magnetic shear

, 2015
Funding: STFC Doctoral Training Grant ST/K502327/1 (Jonathan Hodgson) and STFC Consolidated Grant ST/K000950/1 (Thomas Neukirch)We present an improved formalism for translationally invariant magnetohydrodynamic equilibria with anisotropic pressure and ...
Neukirch, Thomas, T. Neukirch, Hodgson, Jonathan David Brockie, J.D.B. Hodgson   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Enhancing Mn‐Activated Mechanoluminescence via Pressure‐Regulated Local Structure in Centrosymmetric BaZnOS for Dynamic Response Applications

Advanced Science
Self‐recoverable mechanoluminescence (ML), typically observed in non‐centrosymmetric luminescent materials, has recently been reported in centrosymmetric systems such as Mn‐activated BaZnOS.
Hao Wang, Bohao Zhao, Tingting Zhao, Mei Li, Shang Peng, Xuqiang Liu, Yanlong Chen, Jiao An, Sheng Jiang, Yue‐chao Wang, Chuanlong Lin, Wenge Yang   +11 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Retention of high-pressure solution-processable metastable phase to ambience via differential sublattice rigidity for broadband photodetectors

Nature Communications
Materials science exploits only properties that are available at ambience. Therefore, although high-pressure changes the physical state of all condensed matter, most of the extraordinary properties discovered vanish after decompression and cannot be ...
Zhongyang Li, Jue Gong, Zhikai Zhu, Donghao Liu, Qingyang Hu, Yiming Wang, Xuqiang Liu, Shuo Zhou, Hui Luo, Dong Wang, Xingyi Liu, Zengxi Yang, Min Tang, Qingyu Kong, N-Diaye Adama, Kai Zhang, Shuai Yan, Lili Zhang, Xiaohui Zeng, Zhenhai Yu, Wei Xia, Jian Yuan, Mingtao Li, Nana Li, Hongliang Dong, Ziyou Zhang, Haiyun Shu, Yang Ding, Dongbo Wang, Yanfeng Guo, Tao Xu, Lingping Kong, Wenge Yang, Ho-kwang Mao, Gang Liu   +34 more
doaj   +1 more source

The difference between center of mass and center of pressure : A review of human postural control

, 2006
This paper is a review of the relationship between the center of mass (COM) and center of pressure (COP). In the literature, there has been a major misuse of the COP, especially when it is referred to as body sway, inferring that it is the same as the ...
Takada, Yumiko, Takenaka, Yutaka, Goto, Masahiro, Kojima, Yuka, Naruo, Akito, Kikuchi, Naoto, Aoyama, Hiroki, Hamada, Kouta   +7 more
core