Results 61 to 70 of about 175,748,698 (316)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Retention of high-pressure solution-processable metastable phase to ambience via differential sublattice rigidity for broadband photodetectors

Nature Communications
Materials science exploits only properties that are available at ambience. Therefore, although high-pressure changes the physical state of all condensed matter, most of the extraordinary properties discovered vanish after decompression and cannot be ...
Zhongyang Li, Jue Gong, Zhikai Zhu, Donghao Liu, Qingyang Hu, Yiming Wang, Xuqiang Liu, Shuo Zhou, Hui Luo, Dong Wang, Xingyi Liu, Zengxi Yang, Min Tang, Qingyu Kong, N-Diaye Adama, Kai Zhang, Shuai Yan, Lili Zhang, Xiaohui Zeng, Zhenhai Yu, Wei Xia, Jian Yuan, Mingtao Li, Nana Li, Hongliang Dong, Ziyou Zhang, Haiyun Shu, Yang Ding, Dongbo Wang, Yanfeng Guo, Tao Xu, Lingping Kong, Wenge Yang, Ho-kwang Mao, Gang Liu   +34 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Guidance of the Center of Pressure Using Haptic Presentation

CoRR
Accurately instructing posture and the position of the body's center of gravity is challenging. In this study, we propose a system that utilizes haptic feedback to induce the Center of Pressure (CoP) movement. The Wii Balance Board is employed to sense the CoP, and vibration motors are used for haptic feedback.
Yohei Kawasaki, Yuta Sugiura
openaire   +2 more sources

100 Glimpses: A Lion's Tale

, 2023
100 Glimpses is a series of short documentaries produced by the Sight Center of Northwest Ohio. The series explores the organization's history. The Sight Center was founded in 1923 as the Toledo Society for the Blind.
Sight Center of Northwest Ohio (Toledo, Ohio)
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Narrowing band gap chemically and physically: conductive dense hydrocarbon

Communications Materials
Enhancing intermolecular interactions can reduce the band gap energy of organic molecules. Consequently, certain polycyclic aromatic hydrocarbons – typically wide-band-gap insulators – may undergo insulator-to-metal transitions under simple compression ...
Takeshi Nakagawa, Caoshun Zhang, Kejun Bu, Philip Dalladay-Simpson, Martina Vrankić, Sarah Bolton, Dominique Laniel, Dong Wang, Akun Liang, Hirofumi Ishii, Nozomu Hiraoka, Gaston Garbarino, Angelika D. Rosa, Qingyang Hu, Xujie Lü, Ho-kwang Mao, Yang Ding   +16 more
doaj   +1 more source

Synthesis of twin-structured nanodiamond particles

AIP Advances, 2020
Nanodiamonds represent a burgeoning class of carbon nanomaterials that possess favorable physical and chemical properties useful in abrasives, chemocatalysis, biomedicine, etc. Nowadays, the research on nanodiamonds has developed rapidly, with impressive
Pan Ying, Yufei Gao, Bin Zhang, Yingju Wu, Zihe Li, Guoying Gao, Bo Xu, Dongli Yu, Wentao Hu, Zhisheng Zhao, Julong He, Yongjun Tian   +11 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Controllable multicolor emission from initially non-emissive organic molecules by pressure engineering

Nature Communications
Developing smart luminescent materials with off-on switchable responsiveness, which enables dark-to-bright state transitions in response to external stimuli, has garnered great interest across various domains.
Zhihao Xiao, Weibin Wang, Jingkun Yu, Yunfeng Yang, Haifeng Zhu, Siyu Lu, Zhennan Wu, Xinyi Yang, Bo Zou   +8 more
doaj   +1 more source