Results 151 to 160 of about 10,870,630 (259)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Public health diplomacy in Central Asia: a scoping review. [PDF]

Front Public Health
Joshi A, Sharma N, Jha N, Cruz J, Mukashev N, Nazarzoda K, Saliev S, Sharshenova AA, Sarria-Santamera A.   +8 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Retraction: Time series expression pattern of key genes reveals the molecular process of esophageal cancer. [PDF]

Biosci Rep
Wang J, Xie X, Sun Y.
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Discordance Between BMI-Defined Overweight/Obesity and Waist-to-Height Ratio-Defined Central Obesity Among Adults with Type 2 Diabetes in Malawi: A Multicenter Cross-Sectional Study. [PDF]

Diseases
Mboma AT, Mwakilama EP, Kalimbira AA, Cap DM, Duong TV, Hsieh RH.   +5 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Development and internal validation of a nomogram for predicting lymph node metastasis posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma: a single-center retrospective study. [PDF]

Front Endocrinol (Lausanne)
Lu Q, Wei L, Zhang L.
europepmc   +1 more source

Horror Cinema in Belarus: An Unlikely Case Study

Monstrum, 2023
Central Washington University
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source