Results 181 to 190 of about 18,273,946 (366)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Reliability assessment of the non-rigid registration for central incisors movement evaluation based on CBCT registration. [PDF]

Sci Rep
Wu ZX, Shi ZY, Bu WQ, Tang Y, Wu D, Yang H, Ren JC, Tian ZQ, Du SY, Guo YC, Wang F.   +10 more
europepmc   +1 more source

The Monetary Transmission Mechanism in Chile: A Medium-sized Macroeconomics Model [PDF]

Carlos García, Igal Magendzo, Jorge E. Restrepo, Klaus Schmidt-Hebbel, Klaus Schmidt-Hebbel (Series Editor), Norman Loayza (Series Editor), Pablo García, Rómulo A. Chumacero   +7 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Correction: Global burden of disease 2021: particulate matter pollution-attributable burden of upper respiratory infections, otitis media, and lower respiratory infections. [PDF]

Front Public Health
Wei C, Tang Y, Wang Y.
europepmc   +1 more source

From Planning to Implementation: The New UK Central Government Financial Framework

, 2001
Andrew Likierman
openalex   +2 more sources

Review for "Tectonic setting and provenance of Early Cretaceous strata in the footwall of Main Central Thrust, Eastern Nepal: Implications for the archipelago palaeogeography of the <scp>Neo‐Tethys</scp>"

, 2020
Xijun Liu
openalex   +1 more source

Trade Orientation and Labor Market Evolution: Evidence from Chilean Plant-level Data [PDF]

Andrea Tokman R., Jorge Restrepo, Klaus Schmidt-Hebbel (Series Editor), Norman Loayza (Series Editor), Olga Fuentes, Simon Gilchrist   +5 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Bark-cloth clothing of the Bru of Central Vietnam [PDF]

, 2016
Gábor Vargyas
openalex