Results 231 to 240 of about 10,870,630 (259)

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Pain Mechanisms in Fibromyalgia: An Integrative Narrative Review of Central, Peripheral, Neuroimmune, and Psychobiological Factors. [PDF]

Biomedicines
Martins-Alves F, Almeida A.
europepmc   +1 more source

Neurobiological Links Between Endodontic Pain and Temporomandibular Disorders: A Comprehensive Review. [PDF]

Cureus
Katara A, Bathla S, Singh SP, Singh R, Galani M, Kumar D N, Shukla AK, Kashwani R.   +7 more
europepmc   +1 more source

Atypical central neurocytoma with anaplastic histological features in the lateral ventricle of a 37-year-old man. [PDF]

Free Neuropathol
Valkonen M, Bendel P, Rauramaa T, Rantala S.   +3 more
europepmc   +1 more source

Increased Attentive Use Is Linked to More Idiosyncratic Functional Connections. [PDF]

J Neurosci
Demirayak P, Fleming LL, Stewart P, Chua R, Visscher KM.   +4 more
europepmc   +1 more source

Dental Microwear Evidence of Holocene Dietary Variability in the Argentinian Pampas and Paraná Delta. [PDF]

Am J Biol Anthropol
Carvalho MRG, Messineo PG, van Raap MAR, Flensborg G, Martínez G, Scheifler NA, Gonzalez ME, Álvarez MC, Kaufmann CA, Bonomo M, Scabuzzo C, Politis GG, El Zaatari S, Harvati K.   +13 more
europepmc   +1 more source

Lipodystrophy in Central Asia: A Regional Literature Review with a Case Series of Congenital and Acquired Generalized Lipodystrophy. [PDF]

Metabolites
Rakhimzhanova M, Bimurat B, Jangashkarova A, Issabayeva A, Durmanova A, Alzhaxina A, Ivanova-Razumova T, Rapilbekova G.   +7 more
europepmc   +1 more source

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Brain and other central nervous system tumor statistics, 2021

Ca-A Cancer Journal for Clinicians, 2021
Rebecca L. Siegel, Jill S. Barnholtz-Sloan, Carol Kruchko   +2 more
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