Results 241 to 250 of about 18,273,946 (366)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Optimal Management of Indexed and Nominal Debt [PDF]

open access: yes
Fernando Lefort   +4 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

General Equilibrium Analysis of a Fuel Tax Increase in Chile [PDF]

open access: yes
Carlos J. De Miguel   +6 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Mitral regurgitation detection and central/eccentric classification using transformer-based deep learning in multi-view echocardiography. [PDF]

open access: yesJ Appl Clin Med Phys
Zhong X   +12 more
europepmc   +1 more source

Tax Incentives for Retirement Savings: Simulation Results in the Presence of Liquidity Constraints and Heterogeneous Consumers in an OLG-GE Model [PDF]

open access: yes
Klaus Schmidt-Hebbel   +4 more
core  

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