Results 41 to 50 of about 2,116,934 (358)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Transmission mechanisms in HANK: An application to Chile

Latin American Journal of Central Banking
Households in emerging economies are subject to significant income risk and have low access to financial markets. Leveraging multiple administrative microdata sources, this paper documents significant heterogeneity in asset holdings, income, and income ...
Benjamín García, Mario Giarda, Carlos Lizama, Ignacio Rojas   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Bioinformatics analysis of HBV s gene mutation in blood donor

Zhongguo shuxue zazhi
Objective To analyze the infectious indicators, HBV s gene mutations and changes in bioinformatics characteristics of HBV DNA+ /HBsAg- blood donor. Methods A sample of HBV DNA+ /HBsAg- was screened by PCR method, and HBsAg/HBsAb/HBeAg/HBeAb/HBcAb of HBV ...
Jiacheng FAN, Qing LI, Xiuli CHEN, Shixiang LIU, Ye CHEN   +4 more
doaj   +1 more source

Exposures to climate change's physical risks in Chile

Latin American Journal of Central Banking, 2023
We estimate real estate’s exposure in Chile to five weather risks, including labor productivity loss due to heat, fires, floods, drought coastal deterioration as measured by the Chilean Climatic Risk Atlas (ARCLIM) and Climate Impact Explorer (CIE ...
Magdalena Cortina, Carlos Madeira
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Inflation and stock return volatility in selected African countries: A GARCH-MIDAS approach

Scientific African
Amidst persistent inflationary pressures in Africa and central banks raising rates to counter inflation, leading to a shift from stocks to alternative assets and impacting stock return volatility, this paper investigates the influence of inflation on ...
Kamaludeen Muhammad, Abulbashar Saleh, Umar M. Bello, Jeremiah M. Tule, Elijah A. John, Joy E. Edet, Iheanacho Ohiaeri, Chukwuemeka N. Eneanya   +7 more
doaj   +1 more source

Characterization of the Chilean financial cycle, early warning indicators and implications for macro-prudential policies

Latin American Journal of Central Banking, 2021
From the perspective of an emerging country – Chile – we analyze the recommendations of the Basel Committee of Banking Supervision (BCBS) regarding the design and implementation of indicators to guide countercyclical capital buffer (CCyB) policy ...
Juan Francisco Martínez, Daniel Oda
doaj   +1 more source

The European Central Bank [PDF]

, 2006
The establishment of the ECB and with it the launch of the euro has arguably been a unique endeavor in economic history, representing an important experiment in central banking.
Binder, Michael, Wieland, Volker
core