Results 21 to 30 of about 198,147 (243)

Optimized Rapid Disintegrating Tablets produced through Central Composite Design

Current Issues in Pharmacy and Medical Sciences, 2022
The work is aimed at producing fast disintegrating diclofenac potassium tablets to relieve pain and tenderness by applying a quality-by-design approach. Diclofenac potassium (DP) is of BCS class II and has issues of minimal oral bioavailability. This can
Ahad Hindustan Abdul, Chinthaginjala Haranath, Reddy Govardhan, Ganthala Aravind Kumar, Siddhartha Tharun Teja   +4 more
doaj   +1 more source

Optimization of Carotenoids Production from Rhodotorula sp. Strain ATL72 for Enhancing Its Biotechnological Applications

Journal of Fungi, 2022
Rhodotorula yeasts which are known as carotenogenic yeasts have a great industrial value due to their ability to produce carotenoids. In particular, the isolated yeast Rhodotorula sp.
Amira Dyaa, Hoda Soliman, Ahmed Abdelrazak, Bassem N. Samra, Ebtihal Khojah, Atef F. Ahmed, Mohamed A. El-Esawi, Ashraf Elsayed   +7 more
doaj   +1 more source

Effects of Missing Observations on Predictive Capability of Central Composite Designs [PDF]

International Journal on Computational Science & Applications, 2014
Quite often in experimental work, many situations arise where some observations are lost or become unavailable due to some accidents or cost constraints. When there are missing observations, some desirable design properties like orthogonality, rotatability and optimality can be adversely affected.
Yakubu, Yisa, Chukwu, Angela Unna, Adebayo, Bamiduro Timothy, Nwanzo, Amahia Godwin   +3 more
openaire   +2 more sources

Electrocoagulation Process Application in Bilge Water Treatment Using Response Surface Methodology

International Journal of Electrochemical Science, 2014
Marine pollution problems have been noted in increasing manner depending on the increment in sea transportation every succeeding day. Bilge water can be count as one of the main pollution source, which contains petroleum, oil and hydrocarbons in high ...
Kubra Ulucan, Harun Akif Kabuk, Fatih Ilhan, Ugur Kurt   +3 more
doaj   +1 more source

An approach to measuring rotatability in central composite designs

International Journal of Advanced Statistics and Probability, 2015
<p>An approach to measure design rotatability and a measure, that quantifies the percentage of rotatability (from 0 to 100) in the central composite designs are introduced. This new approach is quite different from the ones provided by previous authors which assessed design rotatability by the viewing of tediously obtained contour diagrams.
Emmanuel Ohaegbulem, Polycarp Chigbu
openaire   +2 more sources

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Development of the model to predict the growth of Salmonella spp. in stirred fried rice with crab meat [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2007
Central Composite Design (CCD) was used to study the main factors (temperature, pH, salt concentrations, initial inoculums and incubation time) affecting Salmonella enteritidis growth in stirred fried rice with crab meat. The result obtained from the CCD,
Songamnat Pongsomboon, Sarote Sirisansaneeyakul, Ken Sasaki, Naiyatat Poosaran   +3 more
doaj  

Multivariate optimization of liquid chromatographic conditions for determination of dapagliflozin and saxagliptin, application to an in vitro dissolution and stability studies

Future Journal of Pharmaceutical Sciences, 2021
Background Analytical quality by design driven HPLC method has been optimized for simultaneous estimation of dapagliflozin and saxagliptin in pharmaceutical dosage form.
Sunitha Gurrala, Shiva Raj, C. V. S. Subrahmanyam, Panikumar D. Anumolu   +3 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Chlorogenic Acid: HPLC Quantification and In Vitro Assessment of Proliferative and Migration Effects on Human Dermal Fibroblast Cells

Cumhuriyet Science Journal
Chlorogenic acid (CA) exhibits diverse biological activities, including antioxidant and antiinflammatory effects. This research aims to develop, optimize, and validate an HPLC method to quantify CA in methanol and investigate its in vitro proliferative ...
Burak Bayrak, Fatma Demirkaya Miloğlu, Gülşah Gündoğdu, Leyla Güven, Yücel Kadıoğlu, Abdulbaki Akpınar   +5 more
doaj   +1 more source