Results 1 to 10 of about 153,444 (118)

Enteropathy with impaired membrane digestion and the prospects for cytoprotective therapy

open access: yesТерапевтический архив, 2021
The article describes enteropathy with impaired membrane digestion (EIMD) as a new nosological form. The main clinical manifestation of EIMD is the poor tolerance of food products, in particular carbohydrates and a decrease in the activity of membrane ...
A. I. Parfenov   +6 more
doaj   +1 more source

Pathogenicity and virulence of Streptococcus pneumoniae: Cutting to the chase on proteases

open access: yesVirulence, 2021
Bacterial proteases and peptidases are integral to cell physiology and stability, and their necessity in Streptococcus pneumoniae is no exception. Protein cleavage and processing mechanisms within the bacterial cell serve to ensure that the cell lives ...
Mary E. Marquart
doaj   +1 more source

The secreted FoAPY1 peptidase promotes Fusarium oxysporum invasion

open access: yesFrontiers in Microbiology, 2022
The secretion of peptidases from several pathogens has been reported, but the biological function of these proteins in plant-pathogen interactions is poorly understood. Fusarium oxysporum, a soil-borne plant pathogenic fungus that causes Fusarium wilt in
Hengwei Qian   +4 more
doaj   +1 more source

Dipeptidyl Peptidase IV as a Muscle Myokine

open access: yesFrontiers in Physiology, 2020
Dipeptidyl peptidase IV (DPP-IV) is a unique serine protease that exists in a membrane bound state and in a soluble state in most tissues in the body.
Heidi A. Kluess
doaj   +1 more source

Kinetics of casein hydrolysis by peptidase from Bacillus thuringiensis var. israelensis [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2019
The kinetics of enzyme reaction is generally studied using the Michaelis-Menten equation and various methods of its linearization. Each method has its advantages and drawbacks, so their comparison for determining the kinetics of new enzymes action is ...
O. V. Sevastyanov   +5 more
doaj   +1 more source

Leader peptide removal in lasso peptide biosynthesis based on penultimate isoleucine residue

open access: yesFrontiers in Microbiology, 2023
Lasso peptides are ribosomally synthesized peptides that undergo post-translational modifications including leader peptide removal by B (or the segregated B1 and B2) proteins and core peptide macrolactamization by C proteins to form a unique lariat ...
Yuwei Duan   +11 more
doaj   +1 more source

Japanese Traditional Miso and Koji Making

open access: yesJournal of Fungi, 2021
Miso is a traditional Japanese seasoning paste produced by fermenting soybeans using the power of koji mold. A recent Japanese cohort study has shown that increased consumption of fermented soybean products is associated with a reduced risk of death in ...
Ken-Ichi Kusumoto   +6 more
doaj   +1 more source

Thimet Oligopeptidase Biochemical and Biological Significances: Past, Present, and Future Directions

open access: yesBiomolecules, 2020
Thimet oligopeptidase (EC 3.4.24.15; EP24.15, THOP1) is a metallopeptidase ubiquitously distributed in mammalian tissues. Beyond its previously well characterized role in major histocompatibility class I (MHC-I) antigen presentation, the recent ...
Emer S. Ferro   +2 more
doaj   +1 more source

Particles act as ‘specialty centers’ with expanded enzymatic function throughout the water column in the western North Atlantic

open access: yesFrontiers in Microbiology, 2022
Heterotrophic bacteria initiate the degradation of high molecular weight organic matter by producing an array of extracellular enzymes to hydrolyze complex organic matter into sizes that can be taken up into the cell.
C. Chad Lloyd   +7 more
doaj   +1 more source

Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives

open access: yesBiomolecules, 2020
Caffeic acid (CA) and its derivatives caffeic acid phenethyl ester (CAPE) and chlorogenic acid (CGA) are phenolic compounds of plant origin with a wide range of biological activities. Here, we identify and characterize their inhibitory properties against
Liza Ulčakar, Marko Novinec
doaj   +1 more source

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