Results 41 to 50 of about 233,688 (312)

Fusaoctaxin A, an Example of a Two-Step Mechanism for Non-Ribosomal Peptide Assembly and Maturation in Fungi

Toxins, 2019
Fungal non-ribosomal peptide synthetase (NRPS) clusters are spread across the chromosomes, where several modifying enzyme-encoding genes typically flank one NRPS.
Klaus Ringsborg Westphal, Katrine Amalie Hamborg Nielsen, Rasmus Dam Wollenberg, Mathias Bonde Møllehøj, Simone Bachleitner, Lena Studt, Erik Lysøe, Henriette Giese, Reinhard Wimmer, Jens Laurids Sørensen, Teis Esben Sondergaard   +10 more
doaj   +1 more source

Crystal structures of trypanosoma brucei oligopeptidase B broaden the paradigm of catalytic regulation in prolyl oligopeptidase family enzymes [PDF]

, 2013
Oligopeptidase B cleaves after basic amino acids in peptides up to 30 residues. As a virulence factor in bacteria and trypanosomatid pathogens that is absent in higher eukaryotes, this is a promising drug target.
Canning, Peter, Fülöp, Vilmos, Morty, Rory E., Rea, Dean   +3 more
core   +7 more sources

DmCatD, a cathepsin D-like peptidase of the hematophagous insect Dipetalogaster maxima (Hemiptera: Reduviidae): Purification, bioinformatic analyses and the significance of its interaction with lipophorin in the internalization by developing oocytes [PDF]

, 2018
DmCatD, a cathepsin D-like peptidase of the hematophagous insect Dipetalogaster maxima, is synthesized by the fat body and the ovary and functions as yolk protein precursor. Functionally, DmCatD is involved in vitellin proteolysis.
Arrese, Estela L., Canavoso, Lilian Etelvina, Carlini, Célia Regina R S, Defferrari, Marina S., Fruttero, Leonardo Luis, Leyria, Jimena, Ligabue Braun, Rodrigo, Settembrini, Beatriz Patricia, Soulages, José L.   +8 more
core   +1 more source

OPTIMIZATION OF PARAMETERS OF FERMENTOLYSIS OF PROTEINS IN THE COMPOSITION OF SERUM-PROTEIN CONCENTRATE

Harčova Nauka ì Tehnologìâ, 2018
The food industry is a strategic industry that works quite steadily even during periods of economic crises, providing food security to any state, and is a source of raw material for other industries with a high potential for development, for example, for
N. Tkachenko, L. Lanzhenko, D. Skripnichenko, N. Kuprina, А. Hanicheva   +4 more
doaj   +1 more source

A Multi-season Investigation of Microbial Extracellular Enzyme Activities in Two Temperate Coastal North Carolina Rivers: Evidence of Spatial but Not Seasonal Patterns

Frontiers in Microbiology, 2017
Riverine systems are important sites for the production, transport, and transformation of organic matter. Much of the organic matter processing is carried out by heterotrophic microbial communities, whose activities may be spatially and temporally ...
Avery Bullock, Kai Ziervogel, Sherif Ghobrial, Shannon Smith, Brent McKee, Carol Arnosti   +5 more
doaj   +1 more source

Molecular cloning and characterization of a novel peptidase from Trichinella spiralis and protective immunity elicited by the peptidase in BALB/c mice

Veterinary Research, 2020
In our previous studies, a novel T. spiralis peptidase (TsP) was identified among the excretory/secretory (ES) proteins of T. spiralis intestinal infective larvae (IIL) and T.
Jun Jun Lei, Yuan Yuan Hu, Fang Liu, Shu Wei Yan, Ruo Dan Liu, Shao Rong Long, Peng Jiang, Jing Cui, Zhong Quan Wang   +8 more
doaj   +1 more source

What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands [PDF]

, 2019
Dipeptidyl peptidase 4 (DPP4) is an exopeptidase found either on cell surfaces where it is highly regulated in terms of its expression and surface availability (CD26) or in a free/circulating soluble constitutively available and intrinsically active form.
Aguilar-Pérez, Alexandra, Awad, Mohamed E., Eisa, Nada H., Elmansi, Ahmed M., Fulzele, Sadanand, Hamrick, Mark W., Herberg, Samuel, Hill, William D., Hussein, Khaled A., Isales, Carlos M., Kondrikov, Dmitry, McGee-Lawrence, Meghan E., Periyasamy-Thandavan, Sudharsan, Volkman, Brian F.   +13 more
core   +1 more source

HmrA peptidase

, 2013
Peer ...
Botelho, Tiago O., Gomis-Rüth, F. Xavier   +1 more
openaire   +2 more sources

Cellular functions of gamma-secretase-related proteins [PDF]

, 2006
Amyloid-beta pepticle (A beta) is generated by gamma-secretase, a membrane protein complex with an unusual aspartyl protease activity consisting of the four components presenilin, nicastrin, APH-1 and PEN-2. Presenilin is considered the catalytic subunit
Haass, Christian, Haffner, Christof
core   +1 more source

Unravelling HetC as a peptidase-based ABC exporter driving functional cell differentiation in the cyanobacterium Nostoc PCC 7120

Microbiology Spectrum
The export of peptides or proteins is essential for a variety of important functions in bacteria. Among the diverse protein-translocation systems, peptidase-containing ABC transporters (PCAT) are involved in the maturation and export of quorum-sensing or
Raphaël Rachedi, Véronique Risoul, Maryline Foglino, Yanis Aoudache, Kevin Lang, Stéphanie Champ, Elise Kaplan, Cédric Orelle, Badreddine Douzi, Jean-Michel Jault, Amel Latifi   +10 more
doaj   +1 more source