Insights into the molecular evolution of peptidase inhibitors in arthropods. [PDF]
PLoS ONE, 2017 Peptidase inhibitors are key proteins involved in the control of peptidases. In arthropods, peptidase inhibitors modulate the activity of peptidases involved in endogenous physiological processes and peptidases of the organisms with which they interact ...
Joaquin Alonso, Manuel Martinez
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Fonsecaea pedrosoi Sclerotic Cells: Secretion of Aspartic-Type Peptidase and Susceptibility to Peptidase Inhibitors [PDF]
Frontiers in Microbiology, 2018 Fonsecaea pedrosoi is a dematiaceous fungus and the main causative agent of chromoblastomycosis that is a chronic disease usually affecting the human skin and subcutaneous tissues, which causes deformations and incapacities, being frequently refractory ...
Vanila F. Palmeira +8 more
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Docking simulation between HIV peptidase inhibitors and Trypanosoma cruzi aspartyl peptidase
BMC Research Notes, 2018 Objective The low investment in research, diagnosis and treatment are factors that contribute to the continuity of Chagas’ disease as a neglected tropical diseases (NTDs).
Vanessa V. S. Castilho +10 more
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Enteropathy with impaired membrane digestion and the prospects for cytoprotective therapy
Терапевтический архив, 2021 The article describes enteropathy with impaired membrane digestion (EIMD) as a new nosological form. The main clinical manifestation of EIMD is the poor tolerance of food products, in particular carbohydrates and a decrease in the activity of membrane ...
A. I. Parfenov +6 more
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Pathogenicity and virulence of Streptococcus pneumoniae: Cutting to the chase on proteases
Virulence, 2021 Bacterial proteases and peptidases are integral to cell physiology and stability, and their necessity in Streptococcus pneumoniae is no exception. Protein cleavage and processing mechanisms within the bacterial cell serve to ensure that the cell lives ...
Mary E. Marquart
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The secreted FoAPY1 peptidase promotes Fusarium oxysporum invasion
Frontiers in Microbiology, 2022 The secretion of peptidases from several pathogens has been reported, but the biological function of these proteins in plant-pathogen interactions is poorly understood. Fusarium oxysporum, a soil-borne plant pathogenic fungus that causes Fusarium wilt in
Hengwei Qian +4 more
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, 2020 Two quantum mechanical (QM)-cluster models are built for studying the acylation and deacylation mechanism and kinetics of Streptomyces R61 DD-peptidase with the penicillin G at atomic level detail.
Cheng, Qianyi +3 more
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Dipeptidyl Peptidase IV as a Muscle Myokine
Frontiers in Physiology, 2020 Dipeptidyl peptidase IV (DPP-IV) is a unique serine protease that exists in a membrane bound state and in a soluble state in most tissues in the body.
Heidi A. Kluess
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Kinetics of casein hydrolysis by peptidase from Bacillus thuringiensis var. israelensis [PDF]
The Ukrainian Biochemical Journal, 2019 The kinetics of enzyme reaction is generally studied using the Michaelis-Menten equation and various methods of its linearization. Each method has its advantages and drawbacks, so their comparison for determining the kinetics of new enzymes action is ...
O. V. Sevastyanov +5 more
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Leader peptide removal in lasso peptide biosynthesis based on penultimate isoleucine residue
Frontiers in Microbiology, 2023 Lasso peptides are ribosomally synthesized peptides that undergo post-translational modifications including leader peptide removal by B (or the segregated B1 and B2) proteins and core peptide macrolactamization by C proteins to form a unique lariat ...
Yuwei Duan +11 more
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