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Sleep Medicine, 2021 A multiple sleep latency test (MSLT) with occurrence of sleep onset REM periods (SOREMP) is considered one of the central diagnostic criteria for narcolepsy according to the International Classification of Sleep Disorders, but its sensitivity and specificity have been questioned.
Claudio Bassetti +2 more
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Diagnosis and Treatment of the Central Disorders of Hypersomnolence
2021The central disorders of hypersomnolence (CDH) are lifelong conditions that cause an irrepressible need for sleep during waking hours. Some of these disorders are due to medications or other conditions, but narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH) occur as primary conditions.
Caroline Maness, Lynn Marie Trotti
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Narcolepsy and Other Central Disorders of Hypersomnolence
2018Behavioural advice forms the starting point for the treatment of all central disorders of hypersomnolence. It is also increasingly recognised that the narcolepsy phenotype is broad, including symptoms such as metabolic disturbances potentially fuelling obesity, eating disorders, depression and anxiety.
Paul Reading, Sebastiaan Overeem
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Central disorders of hypersomnolence – A narrative review on current and potential biomarkers
Sleep Medicine ReviewsCentral disorders of hypersomnolence are currently diagnosed in clinical practice from overnight polysomnography and multiple sleep latency test (MSLT). Cerebrospinal fluid (CSF) orexin levels are also a useful confirmatory test for type 1 narcolepsy.
David Wang, Sheila Sivam, Brendon Yee
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0807 Central Disorders of Hypersomnolence in Major Depressive Disorder
SLEEPAbstract Introduction Central disorders of hypersomnia (CDH), characterized by excessive daytime sleepiness, frequently overlap with major depressive disorder (MDD), complicating diagnosis and treatment.
Vishal Saini, Shivani Saini
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Actigraphic assessment of sleep/wake behavior in central disorders of hypersomnolence
Sleep Medicine, 2015To evaluate the reliability of actigraphy to distinguish the features of estimated daytime and nighttime sleep between patients with central disorders of hypersomnolence and healthy controls.Thirty-nine drug-naïve patients with Narcolepsy Type 1, twenty-four drug-naïve patients with Idiopathic Hypersomnia, and thirty age- and sex- matched healthy ...
M. Filardi +5 more
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Narcolepsies and Other Central Hypersomnolence Disorders
Abstract Central hypersomnolence disorders correspond to numerous etiologies of patients with a complaint of excessive daytime sleepiness, excessive quantity of sleep (i.e., hypersomnia), or sleep inertia (i.e., alteration in vigilance following waking up).Yves Dauvilliers, Lucie Barateau
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Cytokines in the Central Disorders of Hypersomnolence (4457)
Neurology, 2021Caroline Maness, LynnMarie Trotti
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