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Idiopathic Hypersomnia—A Dynamic Simulation Model [PDF]

Frontiers in Neurology, 2022
Aims of the study:Commonly used approach to illness assessment focuses on the patient's actual state supplemented by binary records of past events and conditions.
Marek Susta, Karel Šonka, Gustav Bizik, Svojmil Petranek, Sona Nevsimalova   +4 more
doaj   +4 more sources

The Clinical and Economic Burden of Idiopathic Hypersomnia: Results from the Real-World Idiopathic Hypersomnia Total Health Model (RHYTHM) Study [PDF]

Nature and Science of Sleep
Ragy Saad,1 Sarah C Markt,1 Prasheel Lillaney,1 Deb A Profant,1 Douglas S Fuller,2 Elizabeth M Poole,1 Trevor Alvord,3 Patricia Prince,3 Shaina Desai,3 Marisa Whalen,2 Weiyi Ni,1 Jed Black1,4 1Jazz Pharmaceuticals, Palo Alto, CA, USA; 2Jazz ...
Saad R, Markt SC, Lillaney P, Profant DA, Fuller DS, Poole EM, Alvord T, Prince P, Desai S, Whalen M, Ni W, Black J   +11 more
doaj   +2 more sources

Symptom Severity and Treatment Satisfaction in Patients with Idiopathic Hypersomnia: The Real World Idiopathic Hypersomnia Outcomes Study (ARISE) [PDF]

Nature and Science of Sleep, 2023
Logan Douglas Schneider,1 Joanne Stevens,2 Aatif M Husain,3 Diane Ito,4 Douglas S Fuller,5 Phyllis C Zee,6 Wayne Macfadden2 1Stanford University Sleep Medicine Center, Stanford University School of Medicine, Stanford, CA, USA; 2Global Medical Affairs ...
Schneider LD, Stevens J, Husain AM, Ito D, Fuller DS, Zee PC, Macfadden W   +6 more
doaj   +2 more sources

Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study [PDF]

Sleep Science and Practice, 2023
Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD).
Caroline Dodson, Karen Spruyt, Ciaran Considine, Emily Thompson, Osman S. Ipsiroglu, Kanika Bagai, Rosalia Silvestri, Barbara Couvadelli, Arthur S. Walters   +8 more
doaj   +2 more sources

Impairment in Functioning and Quality of Life in Patients with Idiopathic Hypersomnia: The Real World Idiopathic Hypersomnia Outcomes Study (ARISE) [PDF]

Nature and Science of Sleep, 2023
Joanne Stevens,1 Logan D Schneider,2 Aatif M Husain,3 Diane Ito,4 Douglas S Fuller,5 Phyllis C Zee,6 Wayne Macfadden1 1Global Medical Affairs, Jazz Pharmaceuticals, Philadelphia, PA, USA; 2Stanford University Sleep Medicine Center, Stanford University ...
Stevens J, Schneider LD, Husain AM, Ito D, Fuller DS, Zee PC, Macfadden W   +6 more
doaj   +2 more sources

The Clinical and Economic Burden of Idiopathic Hypersomnia and Narcolepsy: A United States Claims-Based Analysis [PDF]

Nature and Science of Sleep
Ragy Saad,1 Sarah C Markt,1 Prasheel Lillaney,1 Deb A Profant,1 Douglas S Fuller,2 Elizabeth M Poole,1 Trevor Alvord,3 Patricia Prince,3 Shaina Desai,3 Marisa Whalen,2 Weiyi Ni,1 Jed Black1,4 1Jazz Pharmaceuticals, Palo Alto, CA, USA; 2Jazz ...
Saad R, Markt SC, Lillaney P, Profant DA, Fuller DS, Poole EM, Alvord T, Prince P, Desai S, Whalen M, Ni W, Black J   +11 more
doaj   +2 more sources

Circadian Modulation of Sleep-Wake Behavior in Patients with Narcolepsy Type 1 and Idiopathic Hypersomnia [PDF]

Nature and Science of Sleep
Franziska Ryser,1,* Ann-Sophie Windirsch,2,3,* Christian R Baumann,3,4 Olivier Lambercy,1 Roger Gassert,1 Esther Werth3,4 1Rehabilitation Engineering Laboratory, Department of Health Sciences and Technology, ETH Zurich, Zurich ...
Ryser F, Windirsch AS, Baumann CR, Lambercy O, Gassert R, Werth E   +5 more
doaj   +2 more sources

Long-Term Treatment of Narcolepsy and Idiopathic Hypersomnia with Low-Sodium Oxybate [PDF]

Nature and Science of Sleep, 2023
Logan D Schneider,1 Anne Marie Morse,2 Michael J Strunc,3 Joyce K Lee-Iannotti,4 Richard K Bogan5 1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA; 2Janet Weis Children’s Hospital, Geisinger ...
Schneider LD, Morse AM, Strunc MJ, Lee-Iannotti JK, Bogan RK   +4 more
doaj   +2 more sources

Single sessions of transcranial direct current stimulation and transcranial random noise stimulation exert no effect on sleepiness in patients with narcolepsy and idiopathic hypersomnia [PDF]

Frontiers in Psychiatry, 2023
BackgroundHypersomnia poses major challenges to treatment providers given the limitations of available treatment options. In this context, the application of non-invasive brain stimulation techniques such as transcranial electrical stimulation (tES) may ...
Michaela Hohenester, Michaela Hohenester, Berthold Langguth, Thomas Christian Wetter, Peter Geisler, Martin Schecklmann, Andreas Reissmann   +6 more
doaj   +2 more sources

A Patient-centric Clinical Trial Design to Comprehensively Evaluate Low-Sodium Oxybate in People with Idiopathic Hypersomnia or Narcolepsy [PDF]

Neurology and Therapy
Introduction Low-sodium oxybate (LXB; Xywav®) is approved to treat idiopathic hypersomnia in adults and excessive daytime sleepiness or cataplexy in individuals aged ≥ 7 years with narcolepsy.
Deborah A. Nichols, Teresa L. Steininger, Douglas S. Fuller, M. Todd Kirby, Emily C. Barker, Marisa Whalen, Jessica K. Alexander, Sarah Akerman, David T. Plante   +8 more
doaj   +2 more sources