Results 41 to 50 of about 2,437 (180)

Diagnosis and management of central hypersomnias

Therapeutic Advances in Neurological Disorders, 2012
Central hypersomnias are diseases manifested in excessive daytime sleepiness (EDS) not caused by disturbed nocturnal sleep or misaligned circadian rhythms.
Karel Sonka, Marek Susta
doaj   +1 more source

Hypersomnia in Guillain-Barré Syndrome: A Co-incidental or an Aetiological Association?

Türk Uyku Tıbbı Dergisi, 2021
Increased daytime sleepiness, hypersomnia, is a very common symptom in the general population and may cause serious problems in their lives. Hypersomnia may be idiopathic or may occur secondary to other aetiologies.
Aylin Bican Demir, Yasemin Dinç, Mustafa Bakar   +2 more
doaj   +1 more source

Precision Medicine for Idiopathic Hypersomnia [PDF]

Sleep Medicine Clinics, 2019
Idiopathic hypersomnia (IH) includes a clinical phenotype resembling narcolepsy (with repeated, short restorative naps), and a phenotype with an excess of sleep, sleep drunkenness, drowsiness, and infrequent long, nonrestorative naps. Sleep tests reflect this heterogeneity. MSLTs are greater than 8 min in 2/3 of the cases and poorly repeatable.
Arnulf, Isabelle, Leu-Semenescu, Smaranda, Dodet, Pauline   +2 more
openaire   +4 more sources

Prevalence of the HLA-DQB1*0602 allele in narcolepsy and idiopathic hypersomnia patients seen at a sleep disorders outpatient unit in São Paulo Prevalência do alelo HLA-DQB1*0602 em pacientes com narcolepsia e hipersonolência idiopática atendidos em ambulatório de sonolência em São Paulo

Brazilian Journal of Psychiatry, 2009
OBJECTIVE: Narcolepsy (with and without cataplexy) and idiopathic hypersomnia, are disorders with common features but with different HLA-DQB1*0602 allele prevalence.
Fernando Morgadinho Santos Coelho, Márcia Pradella-Hallinan, Mario Predazzoli Neto, Lia Rita Azeredo Bittencourt, Sérgio Tufik   +4 more
doaj   +1 more source

Polysomnographic findings in idiopathic hypersomnia patients with migraine and idiopathic hypersomnia patients without headache.

, 2015
Except where otherwise noted, means±SDs are provided.PSG, polysomnography; REM, rapid eye movement; WASO, wake after sleep onset; AHI, apnoea-hypopnoea index; ODI, oxygen desaturation index; PLMS, periodic limb movement in sleep; MSLT, multiple sleep ...
Yuichi Inoue (102157), Shiho Suzuki (115477), Momoyo Murata (801401), Keisuke Suzuki (777222), Masayuki Miyamoto (801397), Ayaka Numao (801402), Shingo Nishida (490699), Kenichi Hayashida (490700), Yoichiro Ueki (490701), Tomoyuki Miyamoto (801398), Kentaro Matsui (801399), Masaki Nakamura (108870), Koichi Hirata (52794), Akira Usui (801400), Yuji Watanabe (801403)   +14 more
core   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

Annals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa, Aurosman Pappus Sahu, David B. Rye, Lynn Marie Trotti, Irina A. Elcheva, Vladimir S. Spiegelman, James R. Connor   +6 more
wiley   +1 more source

Comorbid parasomnias in narcolepsy and idiopathic hypersomnia: more REM than NREM parasomnias

, 2022
International audienceStudy objectives: To assess the frequency, determinants, and clinical impact of clinical rapid eye movement (REM) and non-REM (NREM) parasomnias in adult patients with narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic
Dauvilliers, Yves, Groos, Elisabeth, Franco, Patricia, Lopez, Régis, Barateau, Lucie, Dodet, Pauline, Gales, Ana, Lecendreux, Michel, Arnulf, Isabelle, Drouot, Xavier, Leu-Semenescu, Smaranda, Maranci, Jean-Baptiste   +11 more
core   +1 more source

Neuroimaging in Narcolepsy and Idiopathic Hypersomnia: from Neural Correlates to Clinical Practice

, 2020
Purpose of Review: Clinical presentation of central hypersomnolence disorders, including narcolepsy type 1 and 2 and idiopathic hypersomnia, is often similar, and determining the correct diagnosis remains challenging.
Lammers, Gert Jan, Cross, Nathan, Gool, Jari K., van der Werf, Ysbrand D., Fronczek, Rolf, Dang-Vu, Thien Thanh   +5 more
core   +2 more sources

The melanopsin-mediated pupil response is reduced in idiopathic hypersomnia with long sleep time

Scientific Reports, 2022
Idiopathic hypersomnia (IH), characterized by an excessive day-time sleepiness, a prolonged total sleep time on 24 h and/or a reduced sleep latency, affects 1 in 2000 individuals from the general population.
Héloïse Rach, Ulker Kilic-Huck, Eve Reynaud, Laurence Hugueny, Emilie Peiffer, Virginie Roy de Belleplaine, Fanny Fuchs, Patrice Bourgin, Pierre A. Geoffroy   +8 more
doaj   +1 more source

Salivary biomarkers in sleep‐related disorders

Sleep Research, EarlyView.
Abstract The exploration of salivary biomarkers has emerged as a promising avenue in the diagnosis and management of sleep‐related disorders, such as obstructive sleep apnea (OSA), insomnia, and sleep deprivation. Saliva is a noninvasive biofluid that contains a wealth of biological markers, reflecting both local and systemic physiological changes ...
Chuan Xiang Li, Yi Wang, Ying Ni Lin, Jun Qi Lin, Ya Ru Yan, Xian wen Sun, Liu Zhang, Shi Qi Li, Ning Li, Qing Yun Li   +9 more
wiley   +1 more source