Results 51 to 60 of about 2,437 (180)

Cerebrospinal fluid orexin testing in Australians with narcolepsy type 1

Internal Medicine Journal, EarlyView.
Abstract A clinical diagnosis of narcolepsy type 1 can be challenging, particularly in relation to cataplexy. Despite its specificity, cerebrospinal fluid (CSF) orexin testing is under‐utilised in Australasia. We describe the use of CSF orexin testing in 15 clinically indicated patients from two sleep centres, highlighting its utility in the ...
Mario Fernando, Gianluca Cotta, Samantha Kung, Grace Garden, Jian Eu Tai, Elie Matar, Brendon Yee, Claire Ellender, Sheila Sivam   +8 more
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Electroencephalographic markers of idiopathic hypersomnia : where we are and where we are going

, 2020
Purpose of the review: Idiopathic hypersomnia is a poorly defined nosological entity and has important phenotype heterogeneity. Moreover, diagnosing idiopathic hypersomnia is challenging as patients can report significant symptoms but may not meet ...
Carrier, Julie, Deshaies-Rugama, Anne-Sophie, Desautels, Alex, Lina, Jean-Marc, Montplaisir, Jacques-Yves, Blais, Hélène, Gosselin, Nadia, Thompson, Cynthia   +7 more
core   +1 more source

Compromised Dynamic Cerebral Autoregulation in Patients With Central Disorders of Hypersomnolence

Frontiers in Neurology, 2021
Objective: We aimed to investigate the dynamic cerebral autoregulation (dCA) in patients with central disorders of hypersomnolence during wakefulness.Methods: Thirty-six patients with central disorders of hypersomnolence were divided into three groups ...
Fang Deng, Yanan Zhang, Ran Zhang, Qi Tang, Zhenni Guo, Yudan Lv, Zan Wang, Yi Yang   +7 more
doaj   +1 more source

Profiling the sleep architecture of ageing adults using a seven‐state continuous‐time Markov model

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is a complex biological process regulated by networks of neurons and environmental factors. As one falls asleep, neurotransmitters from sleep–wake regulating neurones work in synergy to control the switching of different sleep states throughout the night. As sleep disorders or underlying neuropathology can manifest as irregular switching,
Jonathon Jacobs, Caitlin E. Martin, Bernard Fuemmeler, Shanshan Chen   +3 more
wiley   +1 more source

Idiopathic Hypersomnia: A Report of Three Adolescent-Onset Cases in a Two-Generation Family

, 2011
Idiopathic hypersomnia is an uncommon sleep disorder characterized by prolonged sleep time and excessive daytime sleepiness without cataplexy. This study concerned a case of familial occurrence.
Emilia Sforza, Soňa Janáčková, Jacques Motte, Serge Bakchine   +3 more
core   +1 more source

Hipersomnia idiopática: desconocida y polimórfica

Revista Médica Clínica Las Condes, 2021
Resumen: La hipersomnia idiopática (HI) es una patología frecuentemente crónica, incapacitante, polimórfica, de etiología y prevalencia desconocida. No existen marcadores biológicos ni test diagnósticos específicos, alcanzando el diagnóstico definitivo ...
Mónica González
doaj   +1 more source

iSPHYNCS: Unsupervised Clustering in Questionnaires and Metadata Reveals Distinct Subtypes in the Narcolepsy Borderland

Journal of Sleep Research, EarlyView.
Study overview and clustering results in the iSPHYNCS cohort. Participant demographics are summarized in a baseline table. Questionnaire data and metadata were processed through an unsupervised clustering pipeline. A Sankey plot illustrates individual assignment across clusters by diagnostic group.
Rafael Morand, Livia Fregolente, Julia van der Meer, Elena S. Wenz, Annina Helmy, Lorenzo Brigato, Jan D. Warncke, Kseniia Zub, Ramin Khatami, Zhongxing Zhang, Sigrid von Manitius, Silvia Miano, Jens Acker, Mathias Strub, Ulf Kallweit, Gert Jan Lammers, Athina Tzovara, Claudio L. A. Bassetti, Stavroula Mougiakakou, Markus H. Schmidt   +19 more
wiley   +1 more source

Investigation of the “Not Better Explained” Diagnosis Criteria in Sleep Disorder Classifications: A Systematic Content Analysis and Critical Review

Journal of Sleep Research, EarlyView.
The “Not Better Explained” (NBE) criterion plays a key role in preventing diagnostic misclassification by structuring causal reasoning in sleep medicine. This systematic content analysis compares the use, wording, and excluded conditions of NBE criteria across the ICSD‐3‐TR and DSM‐5‐TR for ten major sleep disorders.
Jean‐Arthur Micoulaud‐Franchi, Vincent P. Martin, Julien Coelho, Régis Lopez, Pierre‐Alexis Geoffroy, Laure Peter‐Derex, Isabelle Lambert, Charles M. Morin, Clélia Quiles, Christophe Gauld   +9 more
wiley   +1 more source

Autonomic dysfunction in idiopathic hypersomnia: An overlooked association and potential management [PDF]

, 2022
There is a small yet robust body of literature regarding autonomic dysfunction in idiopathic hypersomnia as well as sleep disturbances in postural orthostatic tachycardia syndrome.
Sahni, Ashima Synghal, Adra, Nour, Attarian, Hrayr P., Reddy, Manasa   +3 more
core   +1 more source