Results 71 to 80 of about 2,437 (180)
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT This study aimed to determine the optimal configuration of wrist actigraphy for detecting sleep–wake patterns in adults with varying categories of general motor activity (Aim 1), and to assess its validity in relation to polysomnography (Aim 2).
Agnes M. Baarsen +5 more
wiley +1 more source
Post-COVID central hypersomnia, a treatable trait in long COVID: 4 case reports
Frontiers in NeurologyIntroductionFatigue is the most commonly reported post-COVID symptom. A minority of patients also report excessive daytime sleepiness, which could be a target for treatment.MethodsAmong 530 patients with a post-COVID condition, those with excessive ...
Clémence Morelli-Zaher +12 more
doaj +1 more source
npj Genomic Medicine, 2022 Idiopathic hypersomnia (IH) is a rare, heterogeneous sleep disorder characterized by excessive daytime sleepiness. In contrast to narcolepsy type 1, which is a well-defined type of central disorders of hypersomnolence, the etiology of IH is poorly ...
Taku Miyagawa +43 more
doaj +1 more source
Age at Onset and Delays in Diagnosis of Central Disorders of Hypersomnolence Over the Past 30 Years
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT Patients with narcolepsy type 1 (NT1), type 2 (NT2), idiopathic hypersomnia (IH) usually suffer from symptoms for years, even decades, before being diagnosed. We aimed to assess age at onset, age at diagnosis and changes in the diagnostic delays of these patients from 1990 to 2020 in a single centre.
Zhongxing Zhang +4 more
wiley +1 more source
Sleep and Rhythmic Profile After Pineal Gland Removal in Humans
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT Melatonin, a hormone produced by the pineal gland, is classically described as a central circadian modulator. However, the impact of its absence on circadian rhythmicity in humans remains poorly understood. Pinealectomised patients, in whom melatonin secretion is chronically suppressed, represent a valuable clinical model to investigate the ...
Renata de Andrade Prado Gobetti +7 more
wiley +1 more source
Idiopathic hypersomnia, Kleine–Levin syndrome, and symptomatic hypersomnias
, 2017 Besides obstructive sleep apnea syndrome and narcolepsy, there are a number of other causes of excessive daytime sleepiness, listed in the International Classification of Sleep Disorders, third edition, as central disorders of hypersomnolence.
Michel Billiard, Yves Dauvilliers
core +1 more source
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT Data from the REST‐ON trial were not available before the 2021 American Academy of Sleep Medicine (AASM) clinical practice guideline update, which included a literature review through August 2020. This post hoc analysis from REST‐ON assessed participants who achieved clinically significant improvements on individual AASM clinical significance ...
Luis E. Ortiz +7 more
wiley +1 more source
, 2015 Headache prevalence in the narcolepsy patient, idiopathic hypersomnia patient and control subject groups.
Yuichi Inoue (102157) +14 more
core +1 more source
Sleep disorders and sleep behaviors as predictors of neurodegenerative diseases
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION The impact of sleep disorders (SDs) on incident neurodegenerative disease (NDD) risk has not been comprehensively investigated. METHODS In the UK Biobank cohort, 30,032 participants with SDs (defined by diagnostic codes) and 147,321 without SDs were included.
Taewon Kim +7 more
wiley +1 more source
Prodromal Lewy Body Symptoms and α‐Synuclein Seeding in Idiopathic Olfactory Dysfunction
Movement Disorders Clinical Practice, Volume 13, Issue 2, Page 494-502, February 2026.Abstract Background Early identification of pathological α‐synuclein deposition (αSynD) may improve understanding of Lewy body disorder (LBD) progression and enable timely disease‐modifying treatments. Objectives We investigated αSynD using a seed amplification assay and assessed prodromal LBD symptoms in individuals with idiopathic olfactory ...
Oskar Hoffmann McWilliam +15 more
wiley +1 more source