Results 81 to 90 of about 3,776 (207)
Post-COVID central hypersomnia, a treatable trait in long COVID: 4 case reports
Frontiers in NeurologyIntroductionFatigue is the most commonly reported post-COVID symptom. A minority of patients also report excessive daytime sleepiness, which could be a target for treatment.MethodsAmong 530 patients with a post-COVID condition, those with excessive ...Clémence Morelli-Zaher, Andrea Vremaroiu-Coman, Nicolas Coquoz, Léon Genecand, Marco Altarelli, Alzbeta Binkova, Isabelle Frésard, Pierre-Olivier Bridevaux, Pierre-Olivier Bridevaux, Pierre-Olivier Bridevaux, Grégoire Gex, Grégoire Gex, Grégoire Gex +12 moredoaj +1 more sourceA rare genetic variant in the cleavage site of prepro-orexin is associated with idiopathic hypersomnia
npj Genomic Medicine, 2022 Idiopathic hypersomnia (IH) is a rare, heterogeneous sleep disorder characterized by excessive daytime sleepiness. In contrast to narcolepsy type 1, which is a well-defined type of central disorders of hypersomnolence, the etiology of IH is poorly ...Taku Miyagawa, Susumu Tanaka, Mihoko Shimada, Noriaki Sakai, Kotomi Tanida, Nozomu Kotorii, Tatayu Kotorii, Yu Ariyoshi, Yuji Hashizume, Kimihiro Ogi, Hiroshi Hiejima, Takashi Kanbayashi, Aya Imanishi, Azusa Ikegami, Yuichi Kamei, Akiko Hida, Yamato Wada, Masayuki Miyamoto, Masanori Takami, Hideaki Kondo, Yoshiyuki Tamura, Yukari Taniyama, Naoto Omata, Tomoyuki Mizuno, Shunpei Moriya, Hirokazu Furuya, Mitsuhiro Kato, Kayoko Kato, Jun Ishigooka, Kazuhito Tsuruta, Shigeru Chiba, Naoto Yamada, Masako Okawa, Koichi Hirata, Kenji Kuroda, Kazuhiko Kume, Naohisa Uchimura, Masaaki Kitada, Tohru Kodama, Yuichi Inoue, Seiji Nishino, Kazuo Mishima, Katsushi Tokunaga, Makoto Honda +43 moredoaj +1 more sourceCerebrospinal Fluid Biomarkers of NLRP3 Pathway, Immune Dysregulation, and Neurodegeneration in Parkinson's Disease: A Meta‐Analysis
Movement Disorders, Volume 41, Issue 2, Page 466-477, February 2026.Abstract Background
The activation of the NOD‐, LRR‐ and pyrin domain‐containing protein 3 (NLRP3) inflammasome and associated immune dysregulation is one of the key pathological processes preceding and accompanying α‐synuclein pathology, neuronal damage, and cell death in Parkinson's disease (PD).Alina‐Măriuca Marinescu, Venissa Machado, Gennaro Pagano, Nicoletta Milani Muelhardt, Thomas Kustermann, Eva Zsuzsanna Mracsko, Kathrin Brockmann, Nima Shariati, Judith Anzures‐Cabrera, Bastian Zinnhardt +9 morewiley +1 more sourceValidation of the Idiopathic Hypersomnia Severity Scale in the Czech Republic
Prague Medical ReportWe have verified the eligibility of the Idiopathic Hypersomnia Severity Scale (IHSS) as a basic clinical tool for determining the subjective severity of illness in patients with idiopathic hypersomnia (IH) in the Czech Republic. Total of 37 patients with Jitka Bušková, Eva Miletínová, Tereza Dvořáková, Radana Měrková, Jana Krpešová, Soňa Nevšímalová, Martin Milata, Karolína Galušková, Simona Dostálová, Karel Šonka +9 moredoaj +1 more sourceImpact of Cannabis Smoking on Multiple Sleep Latency Test Outcomes
Journal of Sleep Research, Volume 35, Issue 1, February 2026.ABSTRACT
Our purpose was to evaluate how cannabis smoking influenced multiple sleep latency test (MSLT) outcomes. This was a retrospective study of all adults that had undergone a MSLT at St. Michael's Hospital (Toronto, Ontario, Canada) from 1 January 2008 until 31 December 2018.Kosta Tzanis, Jenna Sykes, Clodagh M. Ryan, Nicholas T. Vozoris +3 morewiley +1 more sourceEfficacy of lisdexamfetamine dimesylate throughout the day in children and adolescents with attention-deficit/hyperactivity disorder:results from a randomized, controlled trial [PDF]
, 2013 Lisdexamfetamine dimesylate (LDX) is a long-acting, prodrug stimulant therapy for patients with attention-deficit/hyperactivity disorder (ADHD). This randomized placebo-controlled trial of an optimized daily dose of LDX (30, 50 or 70 mg) was conducted in Alessandro Zuddas, CK Conners, D Coghill, David R. Coghill, DE May, E Taylor, FA Lopez, G Polanczyk, Isabel Hernández Otero, J Biederman, J Biederman, J Biederman, J Cohen, J Elia, J Ermer, KP Garnock-Jones, LA Adler, Liza A. Squires, M Pennick, M Wolraich, Michel Lecendreux, RA Barkley, Ralf W. Dittmann, Ralph Bloomfield, Richard Civil, RL Findling, RL Findling, S Pliszka, SB Wigal, SW Boellner, T Banaschewski, T Wigal, Tobias Banaschewski, V Simon +33 morecore +3 more sourcesWake EEG and Sleep Hypoxemia Predicts Poor Driving and Vigilance Following Extended Wakefulness in People With OSA
Journal of Sleep Research, Volume 35, Issue 1, February 2026.ABSTRACT
Obstructive sleep apnoea (OSA) is a highly prevalent but heterogeneous condition which makes identifying patients at risk of vigilance and driving impairment clinically challenging. Resting wake electroencephalography (EEG) is associated with vigilance performance in healthy participants.Andrew Vakulin, Garry Cho, David Stevens, Nathaniel S. Marshall, Hannah Openshaw, Delwyn J. Bartlett, Caroline D. Rae, Keith K. H. Wong, R. Doug McEvoy, Ronald R. Grunstein, Angela L. D'Rozario +10 morewiley +1 more sourceSubcutaneous Apomorphine Infusion Initiation Is Associated with Impulse Control Disorder Attenuation in Advanced Parkinson's Disease Patients: Insights from the French NS‐Park Cohort
Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 142-153, January 2026.Abstract Background
Impulse control disorders (ICD) are common non‐motor complications in Parkinson's disease (PD), particularly in patients receiving oral dopamine agonists (DA). Continuous subcutaneous apomorphine infusion (CSAI) is a device‐aided therapy for advanced PD, but its effects on ICD remain underexplored in real‐world settings.Clément Desjardins, Paulo André Dias Bastos, Aymeric Lanore, Christine Brefel‐Courbon, Isabelle Benatru, Caroline Giordana, Anne Doe de Maindreville, Giovanni Castelnovo, Philippe Remy, Luc Defebvre, Claire Thiriez, Stéphane Prange, Jean‐Luc Houeto, Alexandra Samier Foubert, Fabienne Ory‐Magne, Raquel Pinhero Barbosa, Nathalie Bertille, Jean‐Christophe Corvol, Olivier Rascol, Margherita Fabbri, on behalf of the NS‐Part Cohort study group, Jean‐Christophe Corvol, Olivier Rascol, Margherita Fabbri, Wassilios Meissner, Stéphane Thobois, Luc Defebvre, Helene Esperou, Florence Tubach, Yann De Rycke, Layidé Roufai, Dalila Ouazib, Sandra Zarrad, Fatma Khelifi, Florence Tubach, Yann De Rycke, Nathalie Bertille, Vanessa Rousseau, Samuel Tessier, Margherita Fabbri, David Tavel, Dounya Metdaoui, Avigaelle Abitbol, Mathias Antunes, Alexis Brice, Suzanne Lesage, Christelle Tessson, Fanny Casse, Mélanie Ferrien, Guillaume Cogan, Lisa Welment, Thierry Moulin, Wassilios Meissner, Claire Thiriez, Stéphane Thobois, Christian Geny, Solène Frismand, Anne‐Gaëlle Corbille, Caroline Giordana, Giovanni Castelnovo, Isabelle Benatru, Sophie Drapier, David Maltete, Christine Tranchant, Olivier Rascol, Mickael Aubignat, Marie Mongin, Matthieu Bereau, Alexandra Foubert‐Samier, Brice Laurens, Sylvain Vergnet, Thomas Boraud, David Bendetowicz, Jade Sarrabere, Dominique Guehl, Pierre Burbaud, Paul‐Alexandre Pfeiffer, Gilles Defer, Bérengère Debilly, Philippe Derost, Alice Dormeuil, Aimée Petit, Alban Gravier, Vincent Schneider, Lucie Garnier, Nicolas Carriere, Olivier Colin, Philippe Couratier, Chloé Laurencin, Stephane Prange, Paul Jaulent, Bruno Plus, Helene Gervais‐Bernard, Alexandre Eusebio, Frédérique Fluchere, Stephan Grimaldi, Valentin Mira, Tatiana Witjas, Mahmoud Charif, Ophelie Forster, Alix Durand, Pauline Prin, Lucie Hopes, Amory Jardel, Salome Puisieux, Guillemette Clement, Philippe Damier, Tiphaine Rouaud, Pascal Derkinderen, Arthur Lionnet, Adrien De Guilhem De Lataillade, Cosmin Alecu, Charlotte Heraud, Marie De Verdal, Graziella Mangone, Sara Sambin, Aymeric Lanore, Thomas Courtin, Louise‐Laure Mariani, Fouad Khoury, Poornima Menon, Florence Cormier‐Dequaire, Emmanuel Flamand‐Roze, David Grabli, Elodie Hainque, Marie Vidhaillet, Aurélie Meneret, Cécile Delorme, Cendrine Foucard, Florian Von Raison, Alexis Elbaz, Andreas Hartmann, Vincent Leclercq, Theodore Soulier, Daniel Torres, Giulia Coarelli, Giorgia Querin, Fabien Hauw, Margaux Dunoyer, Solène Ansquer, Frederique Leh, Marion Leclercq, Simon Lamy, Guillaume Carey, Guillaume Costentin, Clemence Hardy, Mathieu Anheim, Ouhaid Lagha Boukbiza, Thomas Wirth, Jimmy Voirin, Marie Des Neiges Santin, Thomas Bogdan, Margherita Fabbri, Christine Brefel Courbon Ory‐Magne, Clemence Leung, Hélène Catala, Gabrielle Sill, Raquel Pinheiro Barbosa, Lucy Famer, Lucie Braccagni, Hiba Sifaoui, Juliette Palisson, Kenza Benrahmoune Idrissi, Astrid Causel, Lydie Romeo, Constance Bissessur, Audace Cure‐Martin, Charline Compagne, Sandrine Dupouy, Sandrine Villars, Wei‐Ho Lai, Rachida Bari, Damien Chevanne, Elodie Durand, Isabelle Rieu, Stephane Bernard, Corinne Garsault, Nathalie Meunier, Alexia Cresson, Marine Sgard, Marie Dreano, Justine Montillot, Renaud Massart, Pascale Grebent, Pierre Pelissier, Valérie Santraine, Thomas Gaudin, Pierre Boutet, Cécile Thuilier, Coralie Chalot, Céline Prevost, Hélène Videaud, Justine Picut, Christian Tarrade, Catherine Caire, Hélène Merle, Elise Metereau, Mathilde Millot, Chloe Bernardi, Emilie Favre, Adelaide Jaulent, Laura Mundler, Blandine Dufresne, Eve Benchetrit, Valérie Driss, Alexia Arifi, Maura Rodrigues, Lili Le Monnier, Nathalie Dumont, Virginie Bablon, Régis Frenais, Caroline Herve, Christelle Guimber, Vanessa Ferrier, Elodie David, Christina Faroul, Leslie Fra, Elsa Foucaran, Fatima‐Ezzahra Ennaji, Jeremy Bonetto, Ryad Ladghem‐Chikouche, Le Mickael, Sophie Liot, Sonia Messar, Hamza Salah, Amelie Bernardo, Naoual Serari, Emilie Rabois, Carole David, Zoe Fournier, Margaux Bonnaire‐Verdier, Elise Chevaillier, Françoise Kestens, Rozenn Gourhan, Sandra Lopez‐Alfaro, Jean‐François Houvenaghel, Mélanie Alexandre, Christine Bourdonnais, Linda Vernon, Ahmed Boumediene, Hugo Rummel, Céline Julie, Nadine Longato, Célie Phillipps, Anne Claire Andries‐Ros, Stéphanie Bras, Estelle Harroch, Claudia Gillet, Yoan Herades, Eva Camgrand +249 morewiley +1 more source