Results 81 to 90 of about 3,776 (207)

Post-COVID central hypersomnia, a treatable trait in long COVID: 4 case reports

open access: yesFrontiers in Neurology
IntroductionFatigue is the most commonly reported post-COVID symptom. A minority of patients also report excessive daytime sleepiness, which could be a target for treatment.MethodsAmong 530 patients with a post-COVID condition, those with excessive ...
Clémence Morelli-Zaher   +12 more
doaj   +1 more source

A rare genetic variant in the cleavage site of prepro-orexin is associated with idiopathic hypersomnia

open access: yesnpj Genomic Medicine, 2022
Idiopathic hypersomnia (IH) is a rare, heterogeneous sleep disorder characterized by excessive daytime sleepiness. In contrast to narcolepsy type 1, which is a well-defined type of central disorders of hypersomnolence, the etiology of IH is poorly ...
Taku Miyagawa   +43 more
doaj   +1 more source

Cerebrospinal Fluid Biomarkers of NLRP3 Pathway, Immune Dysregulation, and Neurodegeneration in Parkinson's Disease: A Meta‐Analysis

open access: yesMovement Disorders, Volume 41, Issue 2, Page 466-477, February 2026.
Abstract Background The activation of the NOD‐, LRR‐ and pyrin domain‐containing protein 3 (NLRP3) inflammasome and associated immune dysregulation is one of the key pathological processes preceding and accompanying α‐synuclein pathology, neuronal damage, and cell death in Parkinson's disease (PD).
Alina‐Măriuca Marinescu   +9 more
wiley   +1 more source

Validation of the Idiopathic Hypersomnia Severity Scale in the Czech Republic

open access: yesPrague Medical Report
We have verified the eligibility of the Idiopathic Hypersomnia Severity Scale (IHSS) as a basic clinical tool for determining the subjective severity of illness in patients with idiopathic hypersomnia (IH) in the Czech Republic. Total of 37 patients with
Jitka Bušková   +9 more
doaj   +1 more source

Excessive daytime sleepiness after traumatic brain injury : association with periodic limb movements and REM behavior disorder : case report [PDF]

open access: yes, 2002
Um homem de 52 anos, procurou o Hospital. Universitário de Brasília com queixa de sono agitado. Sua esposa relatava, desde há cerca de 10 anos, intensa movimentação de membros e agressividade em meio a sonhos violentos. Desde então apresentava sonolência
Rodrigues, Raimundo Nonato Delgado   +1 more
core   +2 more sources

Impact of Cannabis Smoking on Multiple Sleep Latency Test Outcomes

open access: yesJournal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT Our purpose was to evaluate how cannabis smoking influenced multiple sleep latency test (MSLT) outcomes. This was a retrospective study of all adults that had undergone a MSLT at St. Michael's Hospital (Toronto, Ontario, Canada) from 1 January 2008 until 31 December 2018.
Kosta Tzanis   +3 more
wiley   +1 more source

Efficacy of lisdexamfetamine dimesylate throughout the day in children and adolescents with attention-deficit/hyperactivity disorder:results from a randomized, controlled trial [PDF]

open access: yes, 2013
Lisdexamfetamine dimesylate (LDX) is a long-acting, prodrug stimulant therapy for patients with attention-deficit/hyperactivity disorder (ADHD). This randomized placebo-controlled trial of an optimized daily dose of LDX (30, 50 or 70 mg) was conducted in
Alessandro Zuddas   +33 more
core   +3 more sources

Wake EEG and Sleep Hypoxemia Predicts Poor Driving and Vigilance Following Extended Wakefulness in People With OSA

open access: yesJournal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT Obstructive sleep apnoea (OSA) is a highly prevalent but heterogeneous condition which makes identifying patients at risk of vigilance and driving impairment clinically challenging. Resting wake electroencephalography (EEG) is associated with vigilance performance in healthy participants.
Andrew Vakulin   +10 more
wiley   +1 more source

Idiopathic Hypersomnia Patients Revealed Longer Circadian Period Length in Peripheral Skin Fibroblasts

open access: yesFrontiers in Neurology, 2018
The vast majority of living organisms have evolved a circadian rhythm of roughly 24 h in adaptation to ever-changing environmental conditions, such as the cycle of light and darkness.
Linus Materna   +6 more
doaj   +1 more source

Subcutaneous Apomorphine Infusion Initiation Is Associated with Impulse Control Disorder Attenuation in Advanced Parkinson's Disease Patients: Insights from the French NS‐Park Cohort

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 1, Page 142-153, January 2026.
Abstract Background Impulse control disorders (ICD) are common non‐motor complications in Parkinson's disease (PD), particularly in patients receiving oral dopamine agonists (DA). Continuous subcutaneous apomorphine infusion (CSAI) is a device‐aided therapy for advanced PD, but its effects on ICD remain underexplored in real‐world settings.
Clément Desjardins   +249 more
wiley   +1 more source

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