Clinical considerations for the diagnosis of idiopathic hypersomnia
Idiopathic hypersomnia is a sleep disorder of neurologic origin characterized by excessive daytime sleepiness, with sleep inertia, long, unrefreshing naps, and prolonged nighttime sleep being key symptoms in many patients. Idiopathic hypersomnia is described in the International Classification of Sleep Disorders, 3rd Edition as a central disorder of ...
Yves Dauvilliers +2 more
exaly +5 more sources
Mononucleosis: A Possible Cause of Idiopathic Hypersomnia [PDF]
Idiopathic hypersomnia (IH) is a rare central hypersomnia of unknown physiopathology. In this study, we determine if the presence of infectious mononucleosis evaluated by serological markers of Epstein Barr virus infection plays a role in this ...
Emilia Sforza +2 more
exaly +4 more sources
Idiopathic Hypersomnia Severity Scale to better quantify symptoms severity and their consequences in idiopathic hypersomnia. [PDF]
To assess the responsiveness of the Idiopathic Hypersomnia Severity Scale (IHSS) to medications and estimate the minimum clinically important difference, to report clinically relevant score ranges, and to confirm its psychometric properties and whether items need to be weighted in drug-free and treated patients with idiopathic hypersomnia (IH).Two ...
Rassu AL +6 more
europepmc +4 more sources
Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia [PDF]
Narcolepsy and idiopathic hypersomnia are central disorders of hypersomnolence accompanied by excessive daytime sleepiness, which are not caused by nocturnal sleep disturbance, sleep deficiency, or circadian rhythm sleep disorders.
Seung-Chul Hong +3 more
doaj +2 more sources
IgG abnormality in narcolepsy and idiopathic hypersomnia. [PDF]
BACKGROUND: A close association between narcolepsy and the Human Leukocyte Antigen (HLA)-DQB1*0602 allele suggests the involvement of the immune system, or possibly an autoimmune process. We investigated serum IgG levels in narcolepsy.
Susumu Tanaka, Makoto Honda
doaj +2 more sources
Clinical and Polysomnographic Comparison between Narcolepsy without Cataplexy and Idiopathic Hypersomnia [PDF]
Background and Objective The aim of this study is to compare the clinical, electrophysiological (Polysomnography, PSG; Multiple Sleep Latency Test, MSLT) and biological data (HLA DQB1*0602 typing) in idiopathic hypersomnia with narcolepsy without ...
Tae Won Kim +7 more
doaj +2 more sources
Idiopathic hypersomnia is an uncommon disorder, but it is serious and needs attention. It is very disabling to patients and can result in motor vehicle accident, difficulty with school or maintaining a job. It can also place stress on families or relationships. It is usually diagnosed by excluding other disorders causing similar symptoms.
Asim Roy, Randip Singh
core +7 more sources
The Prevalence and Characteristics of Primary Headache and Dream-Enacting Behaviour in Japanese Patients with Narcolepsy or Idiopathic Hypersomnia: A Multi-Centre Cross-Sectional Study. [PDF]
Because the prevalence and characteristics of primary headache have yet to be thoroughly studied in patients with hypersomnia disorders, including narcolepsy and idiopathic hypersomnia, we examined these parameters in the Japanese population.In a ...
Keisuke Suzuki +14 more
doaj +2 more sources
A Case of Secondary Hypersomnia Associated with Amlodipine [PDF]
Excessive daytime sleepiness is a symptom which can caused serious problems in patients life and is widely common in general population. It may be occurred depending on drug use and medical conditions. Secondary reasons must be investigated before making
Güray Koç +2 more
doaj +2 more sources
A Patient-centric Clinical Trial Design to Comprehensively Evaluate Low-Sodium Oxybate in People with Idiopathic Hypersomnia or Narcolepsy [PDF]
Introduction Low-sodium oxybate (LXB; Xywav®) is approved to treat idiopathic hypersomnia in adults and excessive daytime sleepiness or cataplexy in individuals aged ≥ 7 years with narcolepsy.
Deborah A. Nichols +8 more
doaj +2 more sources

