Dosing Optimization of Low-Sodium Oxybate in Narcolepsy and Idiopathic Hypersomnia in Adults: Consensus Recommendations [PDF]
Neurology and TherapyIntroduction Low-sodium oxybate (LXB) is approved for treatment of narcolepsy in patients aged 7 years and older and treatment of idiopathic hypersomnia in adults. LXB contains the same active moiety with 92% less sodium than sodium oxybate (SXB). As the
Anne Marie Morse +3 more
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Diagnostic usefulness of 24‐h polysomnography for idiopathic hypersomnia co‐occurring with neurodevelopmental disorders: A case report [PDF]
PCN ReportsBackground Although central disorders of hypersomnolence (CDH) and attention‐deficit/hyperactivity disorder (ADHD) are frequently comorbid, they often remain underdiagnosed, leading to insufficient treatment and sociopsychological outcomes.
Keisuke Kido +4 more
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Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia [PDF]
Sleep Medicine Research, 2023 Narcolepsy and idiopathic hypersomnia are central disorders of hypersomnolence accompanied by excessive daytime sleepiness, which are not caused by nocturnal sleep disturbance, sleep deficiency, or circadian rhythm sleep disorders.
Seung-Chul Hong +3 more
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Diagnostic Value of Psychomotor Vigilance Task for Severe Sleep Inertia in Idiopathic Hypersomnia Versus Other Sleep Disorders Without Sleep Inertia. [PDF]
J Sleep ResDiagnostic Value of PVT for Severe Sleep Inertia in Idiopathic Hypersomnia. ABSTRACT Sleep inertia impairs performance upon awakening and may be assessed using the psychomotor vigilance task (PVT). This study aimed to determine optimal PVT lapse cut‐offs at awakening to objectively measure sleep inertia by comparing patients with idiopathic hypersomnia
Evangelista E +6 more
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Idiopathic Hypersomnia and Depression, the Challenge for Clinicians and Researchers
Prague Medical Report, 2021 The review deals with idiopathic hypersomnia, focusing mostly on the research findings about the presence, onset and severity of excessive daytime sleepiness and depressive symptoms in patients with idiopathic hypersomnia.
Karolína Galušková, Karel Šonka
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The Prevalence and Characteristics of Primary Headache and Dream-Enacting Behaviour in Japanese Patients with Narcolepsy or Idiopathic Hypersomnia: A Multi-Centre Cross-Sectional Study. [PDF]
PLoS ONE, 2015 Because the prevalence and characteristics of primary headache have yet to be thoroughly studied in patients with hypersomnia disorders, including narcolepsy and idiopathic hypersomnia, we examined these parameters in the Japanese population.In a ...
Keisuke Suzuki +14 more
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Characteristics of adults newly diagnosed with idiopathic hypersomnia in the United States
Sleep Epidemiology, 2023 Background: Idiopathic hypersomnia is a debilitating sleep disorder; however, little is known about the clinical presentation of patients receiving this diagnosis.
Ragy Saad +3 more
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Clinical and Polysomnographic Comparison between Narcolepsy without Cataplexy and Idiopathic Hypersomnia [PDF]
Sleep Medicine Research, 2012 Background and Objective The aim of this study is to compare the clinical, electrophysiological (Polysomnography, PSG; Multiple Sleep Latency Test, MSLT) and biological data (HLA DQB1*0602 typing) in idiopathic hypersomnia with narcolepsy without ...
Tae Won Kim +7 more
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IgG abnormality in narcolepsy and idiopathic hypersomnia. [PDF]
PLoS ONE, 2010 BACKGROUND: A close association between narcolepsy and the Human Leukocyte Antigen (HLA)-DQB1*0602 allele suggests the involvement of the immune system, or possibly an autoimmune process. We investigated serum IgG levels in narcolepsy.
Susumu Tanaka, Makoto Honda
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Brain Sciences, 2022 Fatigue, depression, and sleep inertia are frequently underdiagnosed manifestations in narcolepsy and idiopathic hypersomnia. Our cross-sectional study design included diagnostic interview accompanied by assessment instruments and aimed to explore how ...
Sona Nevsimalova +6 more
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