Results 91 to 100 of about 8,482,001 (260)

Transitions In Regional Science – Regions In Transitions: Regional Research In Central Europe

, 2014
There are no exact boundaries of what constitutes Central Europe, but it is nevertheless very evident as a zone of interloping forces stretching across Europe.

core  

Promoting Economic Growth and Resilience in Europe and Central Asia

, 2018
Critical Connections examines how trade, investment, migration, and other linkages among countries drive economic growth in the Europe and Central Asia region.
Gould, David Michael
core   +1 more source

Parasites, Prostitution, and Everyday Vigilance in Socialist Czechoslovakia

Central Europe, 2020
Victoria Skelton, a graduate student at Auburn University, interviews Dr. Christiane Brenner of the Collegium Carolinum about her work on prostitution and vigilance practices in Socialist Czechoslovakia.
Victoria Skelton
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Caught between Continents

Central Europe, 2020
Israel’s idea of its sovereignty over Jewish cultural production has been essential in defining national mythology and self-consciousness ever since its founding as a state in 1948. But by what right does Israel make such claims?
Zachary Kimmel
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Monitoring children’s development in Europe and central Asia with a focus on primary health care: directions for policy and practice

104 p.This publication was developed by the United Nations Children’s Fund (UNICEF) Regional Officefor Europe and Central Asia and the World Health Organization (WHO) Regional Office for Europe.
United Nations Children’s Fund Regional Office for Europe and Central Asia, World Health Organization. Regional Office for Europe   +1 more
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South Slav-Russian Relations in the Last Half of the Nineteenth Century

Central Europe, 2020
This article examines the myth of “eternal friendship” between Bulgarians and Russians and how their mutual failure to understand the other’s motives gave way to resentment, estrangement, and mutual naiveté, straining this supposed natural affinity.
David J Crockett
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Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source