Results 71 to 80 of about 7,950,860 (300)
Central Europe, 2021 This article discusses seventeenth- and eighteenth-century circumstances that adversely affected the armed forces of the Polish-Lithuanian Commonwealth.
Mikolaj Dueholm
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Access to health care for Roma children in Central and Eastern Europe: findings from a qualitative study in Bulgaria [PDF]
, 2009 Background: Despite the attention the situation of the Roma in Central and Eastern Europe has received in the context of European Union enlargement, research on their access to health services is very limited, in particular with regard to child health ...
Blackburn, Clare +11 more
core +1 more source
Central Europe, 2021 Dem Funeralzeremoniell Kaiser Leopolds I. (†1705) wurde in der Forschung bislang nur wenig Aufmerksamkeit zuteil. Dies nimmt die vorliegende Untersuchung zum Anlass, Begräbnis und Begängnis des Kaisers ausführlich zu beschreiben und zu analysieren. Dabei
Lennart Katzenbach
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Public Health in PracticeBackground: Early childhood experiences can promote or adversely affect children's development and wellbeing with lifelong impact. The COVID-19 pandemic disrupted children's and families' lives worldwide. It is important to understand the effect on early
J.M. White +6 more
doaj +1 more source
1958 US Trade Mission to Yugoslavia and the United States' "Wedge" Policy
Central Europe, 2021 This article examines the 1958 US trade mission to Yugoslavia through the lens of technocratic internationalism, which is—borrowing Gabrielle Hetch's definition of the term—a “less visible, but sometimes more powerful means of shaping and reshaping ...
Jacob Smiley
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Into the Void: Governing Finance in Central and Eastern Europe [PDF]
Twenty years after the fall of the iron curtain-which for decades had separated East from West-most countries of Central and Eastern Europe are now members of the European Union; some have even adopted the euro.
Pistor, Katharina
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source