Results 71 to 80 of about 557,081 (304)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Privileged Interfirm/Bank Relationships in Central Europe: Trigger or Trap for Corporate Governance? [PDF]
The paper focuses on the question whether banks and capital markets in Central Europe are capable of exerting a positive influence on enterprise performance at the present stage of the economic transformation.
Gerhard Fink +3 more
core +2 more sources
Notes on Central Europe from Sociological Perspective
, 2007 The following article is an attempt to establish whether the Central Europe of the 20th century is indeed a specific, internally homogenous socio-cultural macro-region. Two mutually complementary approaches were used. One is an analysis of the measure of
Jiří Musil
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Bourbon Ceremony on the Former Habsburg Territory
Central Europe, 2022 This article examines descriptions of the wedding ceremony of Habsburg Archduchess Maria Amalia and Duke Ferdinand of Parma in 1769 and specifically analyzes the decision-making behind her marriage and the symbolism replete in her wedding ceremony ...
Mike Zhou
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Jagiellonian Genesis Tapestries (1553)
Central Europe, 2022 This website explores the Jagiellonian Genesis Tapestries from 1553. It provides an overview of their commission and history and also provides an analysis of the tapestries and the symbolism within them.
Anne Stackpole
doaj
Determinants of House Prices in Central and Eastern Europe [PDF]
This paper studies the determinants of house prices in eight transition economies of central and eastern Europe (CEE) and 19 OECD countries. The main question addressed is whether the conventional fundamental determinants of house prices, such as GDP per
Balazs Egert, Dubravko Mihaljek
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source