Results 61 to 70 of about 8,482,001 (260)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
HIV/AIDS surveillance in Europe 2013: surveillance report
, 2014 xix + 95 p.The HIV epidemic has continued to spread in Europe since 2004 despite advances in medical treatment and new prevention options. In 2013, more than 136 000 new HIV cases were diagnosed across Europe and central Asia, according to the most ...
European Centre for Disease Prevention and Control +1 more
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Notes on Central Europe from Sociological Perspective
, 2007 The following article is an attempt to establish whether the Central Europe of the 20th century is indeed a specific, internally homogenous socio-cultural macro-region. Two mutually complementary approaches were used. One is an analysis of the measure of
Jiří Musil
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Regional Poverty and Income Inequality in Central and Eastern Europe: Evidence from the Luxembourg Income Study [PDF]
poverty, income inequality, regions, Central and Eastern ...
Forster, Michael +2 more
core
Constitutional politics, constitutional texts, and democratic variety in Central and Eastern Europe
, 2012 The article discusses constitution-making processes in Central and Eastern ...
Paul Blokker
core +1 more source
Bourbon Ceremony on the Former Habsburg Territory
Central Europe, 2022 This article examines descriptions of the wedding ceremony of Habsburg Archduchess Maria Amalia and Duke Ferdinand of Parma in 1769 and specifically analyzes the decision-making behind her marriage and the symbolism replete in her wedding ceremony ...
Mike Zhou
doaj