Results 51 to 60 of about 7,950,860 (300)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Supporting Successful Migration in Europe and Central Asia
The Journey Ahead: Supporting Successful Migration in Europe and Central Asia provides an in-depth analysis of international migration in Europe and Central Asia (ECA) and the implications for policy making.
Garrote Sánchez, Daniel +2 more
core +1 more source
Perceived challenges to public health in Central and Eastern Europe: a qualitative analysis. [PDF]
BACKGROUND: There is a major gradient in burden of disease between Central and Eastern Europe compared to Western Europe. Many of the underlying causes and risk factors are amenable to public health interventions.
Rechel, Bernd +19 more
core +3 more sources
Central and Eastern Europe and European security policy: Quo vadis?
This presentation has explored the historical origins and the complexity of building a security policy at European Union level, as well as the major challenges in this area raised by the enlargement of the European Union to Central and Eastern Europe and
ANGHEL, Suzana, DANESCU, Elena
core +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Turning dilemmas into opportunities: a UNU/SCN capacity development network in public nutrition in Central and Eastern Europe [PDF]
Capacity development in nutrition is a process whereby individuals, groups, institutions, organizations and societies enhance their abilities to identify and meet challenges in a sustainable manner. To address these issues, in 2001 the UN System Standing
Pepping, F. +21 more
core +1 more source
New data on the Pseudoscorpion fauna of the caves of the Bakony Mountains, Hungary [PDF]
Examining cave samples from the Bakony Museum of the Hungarian Natural History Museum, Hungary two pseudoscorpion species were found; Chthonius ressli Beier, 1956 and Neobisium carcinoides (Hermann, 1804). C.
János Novák, Csaba Kutasi
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