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Terapevticheskii arkhiv, 2019 Central hypothyroidism is a rare cause of hypothyroidism, consequence of various disorders affecting pituitary (secondary) or hypothalamus (tertiary hypothyroidism). Difficulties in the diagnosis and management of patients are due to the nontypical clinical picture, frequent combination with impaired function of other pituitary hormones, difficulties ...
N A Petunina +2 more
doaj +5 more sources
Indian Journal of Endocrinology and Metabolism, 2011 Central hypothyroidism is defined as hypothyroidism due to insufficient stimulation by thyroid stimulating hormone (TSH) of an otherwise normal thyroid gland. It has an estimated prevalence of approximately 1 in 80,000 to 1 in 120,000. It can be secondary hypothyroidism (pituitary) or tertiary hypothyroidism (hypothalamus) in origin. In children, it is
Vishal Gupta, Marilyn Lee
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Central hypothyroidism: are patients undertreated? [PDF]
European Thyroid Journal, 2020 Introduction Thyroid hormone replacement in central hypothyroidism (CHT) is more difficult than in primary hypothyroidism (PHT), putting patients at risk for inappropriate substitution. In this study, we compared the dosage of thyroid hormone replacement in patients with CHT with that of patients with PHT. In addition, we explored and compared quality
Joke Marlier +3 more
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Central Hypothyroidism in Severe Sepsis [PDF]
Acta Endocrinologica (Bucharest), 2019 A partial or complete deficiency of hormone secretion by pituitary gland (hypopituitarism) is commonly seen after a pituitary apoplexy caused by an infarction of a pituitary adenoma or pituitary hyperplasia (as in Sheehan's syndrome). Hypopituitarism may also follow surgery, when hypovolemia, anticoagulation, fat/air/bone marrow microemboli can provoke
S N, Benea +5 more
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Central Hypothyroidism in Miniature Schnauzers [PDF]
Journal of Veterinary Internal Medicine, 2015 BackgroundPrimary hypothyroidism is a common endocrinopathy in dogs. In contrast, central hypothyroidism is rare in this species.ObjectivesThe objective of this article is to describe the occurrence and clinical presentation of central hypothyroidism in Miniature Schnauzers.
Voorbij, Annemarie MWY +4 more
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Increased Central Arterial Stiffness in Hypothyroidism [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2002 Hypothyroidism is associated with cardiovascular dysfunction. It is increasingly apparent that stiffening of central arteries may lead to increased afterload and cardiac dysfunction. We noninvasively studied the peripheral and central pressure waveforms in 12 untreated hypothyroid patients as well as in 12 age-, sex-, and body mass index-matched ...
K, Obuobie +5 more
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Central Hypothyroidism With Oxcarbazepine Therapy
Pediatric Neurology, 2006 Abnormalities in thyroid function with the use of several antiepileptic medications are thought to result from increased metabolism of thyroid hormone and interference with the hypothalamic-pituitary axis. Oxcarbazepine was developed to attempt to reduce the side effects that have traditionally been observed with antiepileptic drugs that induce the ...
Department of Pediatrics, Division of Endocrinology, University of Florida College of Medicine, Gainesville, Florida ( host institution ) +2 more
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Congenital nystagmus and central hypothyroidism
International Journal of Pediatric Endocrinology, 2015 We observed a male newborn with bilateral nystagmus and central hypothyroidism without hypoprolactinemia due to a deletion of chromosome band Xq26.1q26.2, containing FRMD7 and IGSF1. These two loss-of function mutations are known to cause, respectively, congenital nystagmus and the ensemble of central hypothyroidism, hypoprolactinemia and testicular ...
Reynaert, Nele +2 more
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Central hypothyroidism is a state of thyroid hormone deficiency due to disorders of the pituitary gland, hypothalamus, or hypothalamic–pituitary portal circulation, often due to low thyrotropin-releasing hormone (TRH), insufficient stimulation of normal thyroid-stimulating hormone (TSH), or both.
Huiwen Tan, Yuke Liu, Sumita Cholekho
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Isolated Central Hypothyroidism in Short Stature [PDF]
Pediatric Research, 1995 Mild hypothyroidism can be difficult to diagnose, particularly when it is caused by deficiency of TSH or TSH-releasing hormone (TRH). Such central hypothyroidism occurs most often in association with growth hormone deficiency (GHD). Isolated central hypothyroidism has been considered rare.
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