Pembrolizumab-associated primary hypothyroidism followed by central hypothyroidism: a case report [PDF]
Frontiers in OncologyIntroductionPD-1 inhibitors are widely used anticancer drugs and frequently trigger immune-related adverse events, with thyroid dysfunction as the most prevalent. Suspected isolated central hypothyroidism emerging during PD-1 inhibitor therapy has rarely
Jiawei Sun +3 more
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Succinic semialdehyde dehydrogenase deficiency presenting with central hypothyroidism
Clinical Case Reports, 2021 Central hypothyroidism might be another clinical sign of SSADH deficiency which prompts urinary organic acid screening for GHB in central hypothyroidism patients. Studies on GABA and thyroid hormone interaction might be a concept of a new therapy.
Malak Ali Alghamdi +6 more
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The TRH test provides valuable information in the diagnosis of central hypothyroidism in patients with known pituitary disease and low T4 levels [PDF]
Frontiers in Endocrinology, 2023 ObjectiveTo evaluate the value of the thyrotropin-releasing hormone (TRH) test in the diagnosis of central hypothyroidism (CH) in patients with pituitary disease.MethodsSystematic evaluation of 359 TRH tests in patients with pituitary disease including ...
Sara Ellegaard Christensen +10 more
doaj +2 more sources
Refractory Pericardial Effusion Secondary to Central Hypothyroidism due to Empty Sella Syndrome: A Rare Case Report [PDF]
Clinical Case ReportsRefractory pericardial effusion with a low free T4 but inappropriately normal TSH should prompt evaluation for central hypothyroidism, including pituitary MRI to identify treatable causes such as empty sella syndrome.
Bishal Mandal +6 more
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Identification of a Novel IGSF1 Variant in Two Malaysian Male Siblings with Central Hypothyroidism and Macroorchidism [PDF]
JCRPEImmunoglobulin superfamily member 1 (IGSF1) mutation is the commonest cause of mild to moderate isolated central congenital hypothyroidism and has an X-linked recessive inheritance, primarily affecting males.
Yee Lin Lee +5 more
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Immediate postnatal central hypothyroidism caused by maternal Graves' disease: Importance of early screening [PDF]
Clinical Case Reports, 2022 This report illustrates a case of central hypothyroidism in a newborn immediately after birth caused by maternal Graves' disease. Infants from mothers with Graves' disease require careful examination without waiting for neonatal screening results, even ...
Saho Tochibora +9 more
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Low cholesterol levels are good markers for central hypothyroidism in case with dialysis using roxadustat [PDF]
Clinical Case ReportsKey Clinical Message Recently, hypoxia‐inducible factor prolyl hydroxylase (HIF‐PH) inhibitors have been used for renal anemia, but side effects have also been reported.
Serina Kita +9 more
doaj +2 more sources
Practical and pragmatic usage of T3 in hypothyroidism
Indian Journal of Endocrinology and Metabolism, 2023 Hypothyroidism is one of the common endocrine disorders encountered in clinical practice. Though thyroxine (T4) remains the treatment of choice in most clinical situations, with the recent introduction of oral triiodothyronine (T3) in South Asian ...
Sanjay Kalra +3 more
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Терапевтический архив, 2019 Central hypothyroidism is a rare cause of hypothyroidism, consequence of various disorders affecting pituitary (secondary) or hypothalamus (tertiary hypothyroidism).
N A Petunina +2 more
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Frontiers in Veterinary Science, 2023 Multiple endocrine disorders are uncommon in veterinary medicine, and the disease combination is usually related to hypercortisolism or autoimmunity.
Yeon Chae +6 more
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