Central hypothyroidism is a rare cause of hypothyroidism, consequence of various disorders affecting pituitary (secondary) or hypothalamus (tertiary hypothyroidism).
N A Petunina +2 more
doaj +7 more sources
Succinic semialdehyde dehydrogenase deficiency presenting with central hypothyroidism [PDF]
Central hypothyroidism might be another clinical sign of SSADH deficiency which prompts urinary organic acid screening for GHB in central hypothyroidism patients. Studies on GABA and thyroid hormone interaction might be a concept of a new therapy.
Malak Ali Alghamdi +6 more
doaj +3 more sources
Central hypothyroidism is defined as hypothyroidism due to insufficient stimulation by thyroid stimulating hormone (TSH) of an otherwise normal thyroid gland. It has an estimated prevalence of approximately 1 in 80,000 to 1 in 120,000.
Vishal Gupta, Marilyn Lee
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Central hypothyroidism: are patients undertreated? [PDF]
Introduction Thyroid hormone replacement in central hypothyroidism (CHT) is more difficult than in primary hypothyroidism (PHT), putting patients at risk for inappropriate substitution. In this study, we compared the dosage of thyroid hormone replacement in patients with CHT with that of patients with PHT. In addition, we explored and compared quality
Marlier J +3 more
europepmc +3 more sources
The TRH test provides valuable information in the diagnosis of central hypothyroidism in patients with known pituitary disease and low T4 levels [PDF]
ObjectiveTo evaluate the value of the thyrotropin-releasing hormone (TRH) test in the diagnosis of central hypothyroidism (CH) in patients with pituitary disease.MethodsSystematic evaluation of 359 TRH tests in patients with pituitary disease including ...
Sara Ellegaard Christensen +10 more
doaj +2 more sources
Central hypothyroidism or subclinical hyperthyroidism: can they be confused with each other? [PDF]
Isolated, adult-onset central hypothyroidism is very rare, and its diagnosis can be challenging. A 42-year-old patient was referred for evaluation of a 2.8 cm thyroid nodule.
Mauro Boronat
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Immediate postnatal central hypothyroidism caused by maternal Graves' disease: Importance of early screening [PDF]
This report illustrates a case of central hypothyroidism in a newborn immediately after birth caused by maternal Graves' disease. Infants from mothers with Graves' disease require careful examination without waiting for neonatal screening results, even ...
Saho Tochibora +9 more
doaj +2 more sources
Novel TSHB variant (c.217A>C) causing severe central hypothyroidism and pituitary hyperplasia [PDF]
Biallelic pathological variants in the thyroid stimulating hormone (TSH) subunit β gene (TSHB) result in isolated TSH deficiency and secondary hypothyroidism, a rare form of central congenital hypothyroidism (CCH), with an estimated incidence of 1 in 65 ...
Adam I Kaplan +2 more
doaj +2 more sources
Low cholesterol levels are good markers for central hypothyroidism in case with dialysis using roxadustat [PDF]
Key Clinical Message Recently, hypoxia‐inducible factor prolyl hydroxylase (HIF‐PH) inhibitors have been used for renal anemia, but side effects have also been reported.
Serina Kita +9 more
doaj +2 more sources
Subclinical hypothyroidism or central hypothyroidism—The danger of thyroid function misinterpretation [PDF]
Key Clinical Message Correct interpretation of thyroid function tests is critical to providing appropriate care to patients with suspected thyroid disease.
Oluwaseun Anyiam +2 more
doaj +3 more sources

