Results 71 to 80 of about 1,738,719 (304)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Earthquake declustering in Central Italy
, 2022 Several techniques for earthquake clusters identification have been developed in the literature. They usually rely on different underlying assumptions and lead to different classifications of earthquakes into background events and clustered events. In this study we consider the approach proposed by Varini et al. (2020), in which the seismicity of North-
EVarini, A Peresan
openaire +3 more sources
Hydrogeological map of Italy: the preliminary Sheet N. 348 Antrodoco (Central Italy)
Acque Sotterranee, 2016 The Geological Survey of Italy, Italian National Institute for Environmental Protection and Research is realizing the Sheet N.348 Antrodoco (Central Italy) of the Hydrogeological map of Italy as a cartographical test of the Italian hydrogeological survey
Marco Amanti +7 more
doaj +1 more source
The recombinant protein rSP03B is a valid antigen for screening dog exposure to Phlebotomus perniciosus across foci of canine leishmaniasis [PDF]
, 2017 The frequency of sandfly-host contacts can be measured by host antibody levels against sandfly salivary proteins. Recombinant salivary proteins are suggested to represent a valid replacement for salivary gland homogenate (SGH); however, it is necessary ...
Alten +23 more
core +3 more sources
, 2017 During the first millennium BCE, central Italy was a mosaic of different peoples, each with its own culture and language. Modern-day Latium was settled by Latins and other minor peoples such as Sabines, Faliscans, Hernici, and Volsci. There were other populations in the adjacent regions, too—Umbrians in Umbria, several tribes in Abruzzo, and Picenes in
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Physical and mechanical characterization of the soft pyroclastic rocks forming the Orvieto cliff [PDF]
, 2002 The paper describes the results of laboratory and in situ investigations carried out on weak pyroclastic materials which could be encountered during engineering activities in volcanic regions.
RIBACCHI, Renato +2 more
core
Gli Ungulati in Italia: status, gestione e ricerca scientifica [PDF]
, 2004 Ungulates in Italy: status, management and scientific research. Ungulates in Italy have experienced in the last decade a further increase of their distribution and, possibly, consistence. This trend has been very obvious in the central and northern part
Apollonio, Marco
core +2 more sources
Climatic Variations in Central Italy [PDF]
, 2018 The province of Macerata, Italy, is a topographically complex region which has been little studied in terms of its temperature and precipitation climatology. Temperature data from 81 weather stations and precipitation data from 55 rain gauges were obtained, and, following quality control procedures, were investigated on the basis of 3 standard periods:
Matteo Gentilucci +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source