Results 111 to 120 of about 1,988,517 (312)
Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco +18 more
wiley +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018 Objective To report the diagnosis and treatment of one case of adenoid glioblastoma and investigate the clinicopathological features, diagnosis and differential diagnosis.
Cui-yun SUN, Shi-zhu YU
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich +10 more
wiley +1 more source
Extended Criteria Donors: The Case for Liver Procurement in Donors with a Central Nervous System Malignancy [PDF]
, 2009 Olivier Detry
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source
MALFORMATIONS OF CENTRAL NERVOUS SYSTEM: GENERAL ISSUES [PDF]
, 2013 Malformations of the central nervous system (CNS) encompass a heterogeneous group of congenital anomalies that may be isolated or appear as part of a genetic syndrome.
Alongi,A +9 more
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1122 CENTRAL NERVOUS SYSTEM (CNS) LUPUS ERYTHEMATOSUS (LE) IN CHILDREN [PDF]
, 1978 Ian G. Dresner +4 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source
The influence of modulated sinusoidal current on the state of chromatin from neurons of the cerebral cortex of rats in hypokinesia [PDF]
The biochemical changes under the influence of modulated sinusoidal current in the central nervous system were investigated.
Sokolova, Z. A.
core +1 more source
The renin angiotensin system in the central nervous system [PDF]
, 2011 The first evidences indicating that angiotensin II (ANG II) was a peptide with action on the brain were shown in 1961 when it was found that the intraventricular injection of ANG II induces a centrally mediated pressor response. As a neuropeptide, ANG II
Cavallero, Carmen Susana +2 more
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