Results 101 to 110 of about 24,552,875 (310)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Regeneration in the central nervous system [PDF]

Experimental Gerontology, 2003
Unlike neonatal axons, mammalian adult axons of the CNS do not regenerate after injury. This developmental loss of regenerative capacity, is correlated with the onset of myelination. Likewise, myelin, or myelin-associated components such as Nogo-A and myelin-associated glycoprotein (MAG) inhibit regeneration from older but not younger neurons ...
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Central nervous system tumours

, 2019
Chapter 17 discusses central nervous system tumours, including principles, planning volumes, dose distribution, high- and low-grade glioma, ependymoma, medulloblastoma, germ cell tumours , vestibular (acoustic) schwannoma, pituitary tumours (including ...
Burnet, Neil G., Whitfield, Gillian A., Burton, Kate E., Harris, Fiona, Pinkham, Mark B.   +4 more
core   +1 more source

Central Nervous System Cancers, Version 2.2014 [PDF]

, 2014
The NCCN Guidelines for Central Nervous System Cancers provide multidisciplinary recommendations for the clinical management of patients with cancers of the central nervous system.
Paul Brown, Vrionis, Frank D, Allen K. Sills, Patrick Yung Wen, Louis Burt Nabors, Shonka, Nicole, Matthias Holdhoff, Lode J. Swinnen, Hesser, Deneen, Nicole R. McMillian, Henry Brem, Nicholas Butowski, Lawrence Recht, Frank D. Vrionis, Moots, Paul L, Brown, Paul, Allan Friedman, Hattangadi-Gluth, Jona, Ho, Maria, Deneen Hesser, Mrugala, Maciej M, Mark R. Gilbert, Junck, Larry, Chamberlain, Marc C, Herbert B. Newton, David Tran, Portnow, Jana, Brem, Henry, Tran, David, Paul L. Moots, Nabors, Louis Burt, Gilbert, Mark R, Butowski, Nicholas, Swinnen, Lode J, Newton, Herbert B, Tran, Nam, Larry Junck, Jana Portnow, Maria Ho, Robert A. Fenstermaker, Fenstermaker, Robert A, Wen, Patrick Yung, Ammirati, Mario, Lawson, Ronald, Jay S. Loeffler, Mario Ammirati, Raizer, Jeffrey J, Nicole Shonka, Jeffrey J. Raizer, Ronald Lawson, Shrieve, Dennis C, Marc C. Chamberlain, Jona Hattangadi-Gluth, Sills, Allen K, Recht, Lawrence, Dennis C. Shrieve, Friedman, Allan, Holdhoff, Matthias, DeAngelis, Lisa M, Nam Tran, McMillian, Nicole R, Maciej M. Mrugala, Lisa M. DeAngelis, Loeffler, Jay S   +63 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Primary central nervous system vasculitis: Is it a single disease?

, 2010
Editorial on primary central nervous system ...
Robert D. Brown, Brown, Robert D., Gene G. Hunder, Hunder, Gene G, Carlo Salvarani, SALVARANI, CARLO   +5 more
core   +1 more source

Machine learning models for predicting extended length of stay and hospital charges in nontraumatic subarachnoid hemorrhage

Frontiers in Neurology
BackgroundNontraumatic subarachnoid hemorrhage (SAH) is a critical condition requiring prolonged hospitalization and significant healthcare costs. Identifying factors contributing to extended length of stay (LOS) and predicting associated hospital ...
Di Wu, Di Wu, Sihan Wang, Sihan Wang, Cong Wang, Cong Wang, Yijia Xiang, Lingyu Hao, Zhen Wang, Zhen Wang, Xingye Zhai, Xingye Zhai, Yi Wang, Yi Wang   +13 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Salmonella typhi central nervous system infection [PDF]

, 2007
This report aims to document Salmonella typhi as a cause of central nervous system ...
Dove, Mike G., Weldhagen, Gerhard Frederick   +1 more
core