MicroRNAs of microglia: Wrestling with central nervous system disease [PDF]
Neural Regeneration Research, 2018 Microglia serve as brain-resident myeloid cells that affect cerebral development, ischemia, neurodegeneration, and neuro-viral infection. MicroRNAs play a key role in central nervous system disease through post-transcriptional regulation.
Xiao-Hua Wang, Tian-Long Wang
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B cells in central nervous system disease: diversity, locations and pathophysiology. [PDF]
Nat Rev Immunol, 2022 B cells represent a relatively minor cell population within both the healthy and diseased central nervous system (CNS), yet they can have profound effects.
Jain RW, Yong VW.
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Bioavailable central nervous system disease-modifying therapies for multiple sclerosis [PDF]
Frontiers in Immunology, 2023 Disease-modifying therapies for relapsing multiple sclerosis reduce relapse rates by suppressing peripheral immune cells but have limited efficacy in progressive forms of the disease where cells in the central nervous system play a critical role.
Hans-Peter Hartung +8 more
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Air Pollution and Central Nervous System Disease: A Review of the Impact of Fine Particulate Matter on Neurological Disorders. [PDF]
Front Public Health, 2020 Background: It is widely known that the harmful effects of fine dust can cause various diseases. Research on the correlation between fine dust and health has been mainly focused on lung and cardiovascular diseases.
Kim H, Kim WH, Kim YY, Park HY.
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Immune-Mediated Central Nervous System Disease-Current Knowledge and Recommendations. [PDF]
Top Companion Anim Med, 2019 &NA; Immune‐mediated inflammation is responsible for about 25% of central nervous system disease in dogs. The disease can affect all ages and breeds, but young to middle‐aged small breed dogs are over‐represented for most forms.
Vitale S, Foss K.
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Clinical significance of occult central nervous system disease in adult acute lymphoblastic leukemia. A multicenter report from the Campus ALL Network [PDF]
Haematologica, 2019 In acute lymphoblastic leukemia, flow cytometry detects more accurately leukemic cells in patients' cerebrospinal fluid compared to conventional cytology.
Maria Ilaria Del Principe +24 more
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Disulfidptosis: a new target for central nervous system disease therapy [PDF]
Frontiers in NeuroscienceDisulfidptosis is a pathologic process that occurs under conditions of NADPH deficiency and excess disulfide bonds in cells that express high levels of SLC7A11.
Jing Chang +8 more
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Gait Rehabilitation Device in Central Nervous System Disease: A Review
Journal of Robotics, 2011 Central nervous system diseases cause the gait disorder. Early rehabilitation of a patient with central nervous system disease is shown to be benefit. However, early gait training is difficult because of muscular weakness and those elderly patients who ...
Kazuya Kubo +3 more
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Paraneoplastic Diseases of the Central Nervous System [PDF]
F1000Research, 2020 Paraneoplastic neurological syndromes are nonmetastatic complications of malignancy secondary to immune-mediated neuronal dysfunction or death. Pathogenesis may occur from cell surface binding of antineuronal antibodies leading to dysfunction of the target protein, or from antibodies binding against intracellular antigens which ultimately leads to cell
Jonathan R. Galli +2 more
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Frontiers in Immunology, 2021 Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody, showed its therapeutic efficacy on neuromyelitis optica spectrum disorder (NMOSD).
Ye Liu +12 more
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