Results 141 to 150 of about 760,593 (172)
Large‐Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain
This study delineates both common and site‐specific proteins linked to various chronic pain conditions, elucidating their implications across molecular pathways and health status. These findings, particularly those proteins with genetic causal links to pain or predictive capabilities, have the potential to significantly benefit both research and ...
Ze‐Yu Li+17 more
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Central nervous system lyme disease [PDF]
Nervous system infection with Borrelia burgdorferi frequently causes meningitis and rarely causes encephalomyelitis. Altered cognitive function also can occur in the absence of central nervous system infection. Recently developed serodiagnostic tools, such as the C6 assay, and appropriate use of Western blotting promise to improve diagnostic accuracy ...
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Inflammatory Diseases of the Central Nervous System
Neurologic Clinics, 2021Pediatric neuroinflammatory conditions are a complex group of disorders with a wide range of clinical presentations. Patients can present with a combination of focal neurologic deficits, encephalopathy, seizures, movement disorders, or psychiatric manifestations.
Eyal Muscal+2 more
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Transglutaminase and diseases of the central nervous system
Frontiers in Bioscience, 2005Alzheimer's disease, Parkinson's disease and diseases of expanded polyglutamine are associated with insoluble protein aggregates and neuronal death. A role for transglutaminase in the stabilization of these aggregates has been proposed. Diseases of polyglutamine expansion have been the most thoroughly investigated and a large body of studies supports ...
Hoffner, Guylaine, Djian, Philippe
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Amyloid in central nervous system disease
Clinical Neurology and Neurosurgery, 1990A review is presented of diseases of the central nervous system associated with amyloid deposition. The name amyloid is given to substances with particular physical characteristics which are independent of the chemical constitution of the proteins in the substance.
J. Haan, R.A.C. Roos
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Central nervous system Lyme disease
Seminars in Pediatric Infectious Diseases, 2003Lyme disease is a disease caused by the spirochete, Borrelia burgdorferi. It is transmitted to humans via a bite from an infected tick. It has several classic stages or categories of illness, including early localized disease, early disseminated disease, and late disease.
Lucy Pontrelli, Sharon Nachman
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Ergothioneine and central nervous system diseases
Neurochemical Research, 2022Ergothioneine (ERGO) is a thiol contained in the food that exhibits an excellent antioxidant effect similar to that of glutathione. Although mammals lack a biosynthetic pathway for ERGO, the carnitine/organic cation transporter OCTN1/SLC22A4, which transports ERGO in vivo, is expressed throughout the body, and ERGO is distributed to various organs ...
Noritaka Nakamichi+2 more
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Batokine in Central Nervous System Diseases
Molecular Neurobiology, 2023Brown adipose tissue (BAT) is a special type of fat tissue in mammals and is also a key endocrine organ in the human body. Batokine, the endocrine effector of BAT, plays a neuroprotective role and improves the prognosis by exerting anti-apoptotic and anti-inflammatory effects, as well as by improving vascular endothelial function and other mechanisms ...
Ming Shen+3 more
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Granulomatous Diseases of the Central Nervous System
Current Neurology and Neuroscience Reports, 2022To discuss the pathophysiology, key clinical features, necessary diagnostic evaluation, and current treatment regimens for granulomatous diseases of the central nervous system.The diagnosis and management of granulomatous disease of the central nervous system has been revolutionized by advances in diagnostic imaging.
Braden, Dasovic+2 more
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Neurogenesis in Diseases of the Central Nervous System
Stem Cells and Development, 2006Neurogenesis is altered in ageing, and diseases of the central nervous system (CNS) such as neurodegenerative disorders. We discuss the process of neurogenesis, its relevance for disorders of the CNS, the dynamic nature of neurogenesis, how and why it may be abnormal in ageing, and disease, and possibilities to ameliorate abnormal neurogenesis in ...
Roger A. Barker+2 more
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