Results 141 to 150 of about 760,593 (172)

Large‐Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain

open access: yesAdvanced Science, EarlyView.
This study delineates both common and site‐specific proteins linked to various chronic pain conditions, elucidating their implications across molecular pathways and health status. These findings, particularly those proteins with genetic causal links to pain or predictive capabilities, have the potential to significantly benefit both research and ...
Ze‐Yu Li   +17 more
wiley   +1 more source

Central nervous system lyme disease [PDF]

open access: possibleCurrent Infectious Disease Reports, 2004
Nervous system infection with Borrelia burgdorferi frequently causes meningitis and rarely causes encephalomyelitis. Altered cognitive function also can occur in the absence of central nervous system infection. Recently developed serodiagnostic tools, such as the C6 assay, and appropriate use of Western blotting promise to improve diagnostic accuracy ...
openaire   +4 more sources

Inflammatory Diseases of the Central Nervous System

Neurologic Clinics, 2021
Pediatric neuroinflammatory conditions are a complex group of disorders with a wide range of clinical presentations. Patients can present with a combination of focal neurologic deficits, encephalopathy, seizures, movement disorders, or psychiatric manifestations.
Eyal Muscal   +2 more
openaire   +3 more sources

Transglutaminase and diseases of the central nervous system

Frontiers in Bioscience, 2005
Alzheimer's disease, Parkinson's disease and diseases of expanded polyglutamine are associated with insoluble protein aggregates and neuronal death. A role for transglutaminase in the stabilization of these aggregates has been proposed. Diseases of polyglutamine expansion have been the most thoroughly investigated and a large body of studies supports ...
Hoffner, Guylaine, Djian, Philippe
openaire   +5 more sources

Amyloid in central nervous system disease

Clinical Neurology and Neurosurgery, 1990
A review is presented of diseases of the central nervous system associated with amyloid deposition. The name amyloid is given to substances with particular physical characteristics which are independent of the chemical constitution of the proteins in the substance.
J. Haan, R.A.C. Roos
openaire   +3 more sources

Central nervous system Lyme disease

Seminars in Pediatric Infectious Diseases, 2003
Lyme disease is a disease caused by the spirochete, Borrelia burgdorferi. It is transmitted to humans via a bite from an infected tick. It has several classic stages or categories of illness, including early localized disease, early disseminated disease, and late disease.
Lucy Pontrelli, Sharon Nachman
openaire   +3 more sources

Ergothioneine and central nervous system diseases

Neurochemical Research, 2022
Ergothioneine (ERGO) is a thiol contained in the food that exhibits an excellent antioxidant effect similar to that of glutathione. Although mammals lack a biosynthetic pathway for ERGO, the carnitine/organic cation transporter OCTN1/SLC22A4, which transports ERGO in vivo, is expressed throughout the body, and ERGO is distributed to various organs ...
Noritaka Nakamichi   +2 more
openaire   +2 more sources

Batokine in Central Nervous System Diseases

Molecular Neurobiology, 2023
Brown adipose tissue (BAT) is a special type of fat tissue in mammals and is also a key endocrine organ in the human body. Batokine, the endocrine effector of BAT, plays a neuroprotective role and improves the prognosis by exerting anti-apoptotic and anti-inflammatory effects, as well as by improving vascular endothelial function and other mechanisms ...
Ming Shen   +3 more
openaire   +2 more sources

Granulomatous Diseases of the Central Nervous System

Current Neurology and Neuroscience Reports, 2022
To discuss the pathophysiology, key clinical features, necessary diagnostic evaluation, and current treatment regimens for granulomatous diseases of the central nervous system.The diagnosis and management of granulomatous disease of the central nervous system has been revolutionized by advances in diagnostic imaging.
Braden, Dasovic   +2 more
openaire   +2 more sources

Neurogenesis in Diseases of the Central Nervous System

Stem Cells and Development, 2006
Neurogenesis is altered in ageing, and diseases of the central nervous system (CNS) such as neurodegenerative disorders. We discuss the process of neurogenesis, its relevance for disorders of the CNS, the dynamic nature of neurogenesis, how and why it may be abnormal in ageing, and disease, and possibilities to ameliorate abnormal neurogenesis in ...
Roger A. Barker   +2 more
openaire   +3 more sources

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