Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth
Advanced Functional Materials, EarlyView.Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung +8 more
wiley +1 more source
Regulation of Glial Function by Noncoding RNA in Central Nervous System Disease. [PDF]
Neurosci Bull, 2023 Bai Y +8 more
europepmc +1 more source
A neutralization-resistant Theiler's virus variant produces an altered disease pattern in the mouse central nervous system [PDF]
, 1989 Andreas Zurbriggen, Robert S. Fujinami
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Advanced Functional Materials, EarlyView.Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu +7 more
wiley +1 more source
Disseminated hydatid disease in the orbit and central nervous system [PDF]
International Journal of Ophthalmology, 2021 Ming-Shen Ma +4 more
doaj +1 more source
Protein Tyrosine Phosphatase Receptor Type Z in Central Nervous System Disease. [PDF]
Int J Mol Sci, 2022 Nagai K, Fujii M, Kitazume S.
europepmc +1 more source
Neuropeptide-induced hypothermia and the course of central nervous system disease mediated by temperature-sensitive mutants of vesicular stomatitis virus [PDF]
, 1985 Sharon C. Doll, Terry C. Johnson
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Inflammatory demyelinating diseases of the central nervous system
, 2018 Inflammatory demyelinating diseases are a heterogeneous group of disorders, which occur against the background of an acute or chronic inflammatory process. The pathologic hallmark of multiple sclerosis (MS) is the presence of focal demyelinated lesions with partial axonal preservation and reactive astrogliosis.
Hans Lassmann, Romana Höftberger
openaire +3 more sources
Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa +5 more
wiley +1 more source
The Role of Brain-Derived Neurotrophic Factor Signaling in Central Nervous System Disease Pathogenesis. [PDF]
Front Hum Neurosci, 2022 Dou SH, Cui Y, Huang SM, Zhang B.
europepmc +1 more source