Results 281 to 290 of about 1,782,711 (374)

Gap junction protein beta 1 (GJB1 ) mutations and central nervous system symptoms in X-linked Charcot-Marie-Tooth disease

, 2003
Hiroshi Takashima, M. Nakagawa, Fujio Umehara, Keiko Hirata, Masahito Suehara, H. Mayumi, K. Yoshishige, Wataru Matsuyama, Masanori Saito, Manabu Jonosono, Kimiyoshi Arimura, Mitsuhiro Osame   +11 more
openalex   +1 more source

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

Advanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa, Jiali Wang, Mengzhao Xun, Jessica M. Rosenholm, Wuqing Wang, Yilai Shu, Hongbo Zhang   +6 more
wiley   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Association of Chlamydia pneumoniae with central nervous system disease

, 2003
Charles W. Stratton, Subramaniam Sriram
openalex   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Expression of microRNAs in cerebrospinal fluid of dogs with central nervous system disease. [PDF]

Acta Vet Scand, 2018
Marioni-Henry K, Zaho D, Amengual-Batle P, Rzechorzek NM, Clinton M.   +4 more
europepmc   +1 more source

Social and hygienic aspects of a disease incidence and treatment results of patients with primary tumors of the central nervous system in the Republic of Tatarstan

, 2003
В. И. Данилов, A. G. Alexejev, Ш. М. Вахитов   +2 more
openalex   +2 more sources

Wearable Systems of Reconfigurable Microneedle Electrode Array for Subcutaneous Multiplexed Recording of Myoelectric and Electrochemical Signals

Advanced Science, EarlyView.
A reconfigurable microneedle electrode array integrated system is developed for minimally invasive and transdermal monitoring of subcutaneous electromyography, reactive oxygen species, and pH values. By assembling discrete thumbtack‐shaped microneedles into an array, the system enables multi‐parameter detection with single‐microneedle resolution.
Zhengjie Liu, Chuanjie Yao, Xingyuan Xu, Xinshuo Huang, Shuang Huang, Shantao Zheng, Tao Zhang, Yan Li, Fanmao Liu, Yuxiang Wu, Jing Liu, Hui‐jiuan Chen, Xi Xie   +12 more
wiley   +1 more source

Lack of Efficacy of High-Titered Immunoglobulin in Patients with West Nile Virus Central Nervous System Disease. [PDF]

Emerg Infect Dis, 2019
Gnann JW, Agrawal A, Hart J, Buitrago M, Carson P, Hanfelt-Goade D, Tyler K, Spotkov J, Freifeld A, Moore T, Reyno J, Masur H, Jester P, Dale I, Li Y, Aban I, Lakeman FD, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group.   +18 more
europepmc   +1 more source