Results 41 to 50 of about 1,782,711 (374)

Inflammatory Disease of the Central Nervous System

open access: yesVeterinary Clinics of North America: Small Animal Practice, 1988
Inflammatory diseases involving the central nervous system can be difficult to diagnose and frustrating to treat. The clinician can maximize successful treatment of these patients by recognizing the clinical signs in the early stages of disease, following a logical diagnostic plan to identify the specific etiologic agent involved, and formulating an ...
openaire   +3 more sources

Antibody-mediated central nervous system diseases [PDF]

open access: yesBrain and Neuroscience Advances, 2018
Antibody-mediated central nervous system diseases are a relatively new area of clinical neuroscience with growing impact. Their recognition has challenged the dogma of the blood–brain barrier preventing antibody access into the central nervous system. The antibodies discovered so far are mainly against neurotransmitter receptors (e.g.
Angela Vincent   +4 more
openaire   +3 more sources

Role of Thrombin in Central Nervous System Injury and Disease

open access: yesBiomolecules, 2021
Thrombin is a Na+-activated allosteric serine protease of the chymotrypsin family involved in coagulation, inflammation, cell protection, and apoptosis. Increasingly, the role of thrombin in the brain has been explored. Low concentrations of thrombin are
Nathan A. Shlobin   +4 more
doaj   +1 more source

Infectious diseases of the central nervous system

open access: yesVeterinary Clinics of North America: Small Animal Practice, 2005
Neurologic disease is seen commonly in cats, with infectious causes accounting for 30-45% of cases. However, since a specific infection cannot be identified in 12-40% of these cases, it is essential that we try to understand these cases better in the hope that we can eventually identify the cause(s), and so determine how best to treat and/or prevent ...
openaire   +3 more sources

Erdheim-Chester disease presenting at the central nervous system

open access: yesAutopsy and Case Reports, 2021
Erdheim-Chester disease is a rare non-Langerhans cell histiocytosis (LCH) that affects different body systems. It was recently recognized as a neoplastic disorder after identifying an activating mutation of the MAPK pathway. Neurological presentations of
Sydney Fasulo   +9 more
doaj  

Latent Space Analysis of VAE and Intro-VAE applied to 3-dimensional MR Brain Volumes of Multiple Sclerosis, Leukoencephalopathy, and Healthy Patients [PDF]

open access: yesarXiv, 2021
Multiple Sclerosis (MS) and microvascular leukoencephalopathy are two distinct neurological conditions, the first caused by focal autoimmune inflammation in the central nervous system, the second caused by chronic white matter damage from atherosclerotic microvascular disease.
arxiv  

HIV-1-related central nervous system disease: current issues in pathogenesis, diagnosis, and treatment.

open access: yesCold Spring Harbor Perspectives in Medicine, 2012
HIV-associated central nervous system (CNS) injury continues to be clinically significant in the modern era of HIV infection and therapy. A substantial proportion of patients with suppressed HIV infection on optimal antiretroviral therapy have impaired ...
S Spudich, F. González-Scarano
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Mechanics of Morphogenesis in Neural Development: in vivo, in vitro, and in silico [PDF]

open access: yesarXiv, 2022
Morphogenesis in the central nervous system has received intensive attention as elucidating fundamental mechanisms of morphogenesis will shed light on the physiology and pathophysiology of the developing central nervous system. Morphogenesis of the central nervous system is of a vast topic that includes important morphogenetic events such as ...
arxiv  

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