Results 61 to 70 of about 1,782,711 (374)

Demyelinating Disease? Central Nervous System Lymphoma?

Türk Nöroloji Dergisi, 2008
Scientific backgound: Primary lymphomas of the central nervous system (CNS) consist of about 1% of brain tumors. Primary central nervous system lymphoma (PSSSL) is a non-Hodgkin’s lymphoma restricted to the nervous system.
Ufuk Ergün, Abidin Erdal, Bahar Say, Ruhat Karahan, Levent İnan, Figen Söylemezoğlu, Hakan Oruçkaptan   +6 more
doaj  

Searching for clues: tracking the pathogenesis of human immunodeficiency virus central nervous system disease by use of an accelerated, consistent simian immunodeficiency virus macaque model.

Journal of Infectious Diseases, 2002
An accelerated model of human immunodeficiency virus central nervous system disease was developed in which more than 90% of infected macaques develop typical simian immunodeficiency virus (SIV) encephalitis with neuronal dysfunction by postinoculation ...
J. Mankowski, J E Clements, M. Zink
semanticscholar   +1 more source

Role of Exosomes in Central Nervous System Diseases [PDF]

Frontiers in Molecular Neuroscience, 2019
There are many types of intercellular communication, and extracellular vesicles are one of the important forms of this. They are released by a variety of cell types, are heterogeneous, and can roughly be divided into microvesicles and exosomes according to their occurrence and function.
Wanying Liu, Wanying Liu, Wanying Liu, Xiaodan Bai, Xiaodan Bai, Xiaodan Bai, Ao Zhang, Juanjuan Huang, Juanjuan Huang, Juanjuan Huang, Shixin Xu, Shixin Xu, Junping Zhang   +12 more
openaire   +4 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Central nervous system Listeria monocytogenes infection mimicking central nervous system idiopathic inflammatory demyelinating disease

Infection and Drug Resistance, 2019
Rui Xu,1,* Yang Bai,2,* Chunmei Duan,1 Shifu Zhao,1 Xiaoyan Chen,1 Qingwu Yang1 1Department of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China ...
Xu R, Bai Y, Duan C, Zhao S, Chen X, Yang Q   +5 more
doaj  

Multiple Sclerosis disease: a computational approach for investigating its drug interactions [PDF]

arXiv, 2020
Multiple Sclerosis (MS) is a chronic and potentially highly disabling disease that can cause permanent damage and deterioration of the central nervous system. In Europe it is the leading cause of non-traumatic disabilities in young adults, since more than 700,000 EU people suffer from MS. Although recent studies on MS pathophysiology have been provided,
arxiv  

IMMUNOPATHOGENESIS OF ACUTE CENTRAL NERVOUS SYSTEM DISEASE PRODUCED BY LYMPHOCYTIC CHORIOMENINGITIS VIRUS

Journal of Experimental Medicine, 1972
Lymphocytic choriomeningitis (LCM) virus carriers were established by intracerebral inoculation of adult BALB/c mice followed by a single dose of cyclophosphamide (CY) (150 mg/kg) 3 days after infection, and by intracerebral injection within 24 hr of ...
D. Gilden, G. A. Cole, N. Nathanson
semanticscholar   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Role of Mycobacterium tuberculosis pknD in the Pathogenesis of central nervous system tuberculosis

BMC Microbiology, 2012
Background Central nervous system disease is the most serious form of tuberculosis, and is associated with high mortality and severe neurological sequelae.
Be Nicholas A, Bishai William R, Jain Sanjay K   +2 more
doaj   +1 more source

The Glymphatic System in Central Nervous System Health and Disease: Past, Present, and Future.

Annual Review of Pathology, 2018
The central nervous system (CNS) is unique in being the only organ system lacking lymphatic vessels to assist in the removal of interstitial metabolic waste products.
Benjamin A. Plog, M. Nedergaard
semanticscholar   +1 more source