Results 281 to 290 of about 1,580,164 (331)

Targeting sialylation to treat central nervous system diseases.

TIPS - Trends in Pharmacological Sciences, 2021
Sialic acid-binding immunoglobulin-type lectins (SIGLECs) are membrane receptors that are preferentially expressed on immune cells and recognize sialylated proteins, lipids, and RNA.
J. Lünemann, S. von Gunten, H. Neumann
semanticscholar   +1 more source

Pediatric Central Nervous System Demyelinating Diseases

Continuum, 2019
This article provides an up-to-date summary of the categories, diagnosis, and management of pediatric demyelinating disorders.Understanding of the diverse spectrum of pediatric demyelinating disorders, including monophasic and multiphasic forms, has improved.
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Central nervous system AIDS – related diseases

Acta Neurochirurgica, 2004
The neurological complications of HIV contribute importantly to patient morbidity and mortality. Major common AIDS-related CNS diseases are ADC, metabolic encephalopaties, CMV encephalitis, TE, PCNSL, PML, criptococcal meningitis, and aseptic meningitis.
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The Complement System in Central Nervous System Diseases

Immunologic Research, 2001
The activation of complement system is an important factor participating in inflammatory, neurodegenerative, and cerebrovascular diseases. Astrocytes and neurons are able to synthesize complement components. Myelin and oligodendrocyte (OLG) activate the classical pathway of complement in vitro in the absence of antibodies. Sublytic C5b-9 in the absence
H, Rus, F, Niculescu
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Central Nervous System Manifestations of Lyme Disease

Archives of Neurology, 1989
We studied six patients with central nervous system manifestations of Lyme disease. Weeks to years after the initial infection, behavioral changes, ataxia, and/or weakness in bulbar or peripheral muscles developed. Four of the six patients had a lymphocytic pleocytosis in the cerebrospinal fluid, and two of them had magnetic resonance imaging scans ...
A R, Pachner, P, Duray, A C, Steere
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Lyme Disease Mimicking Central Nervous System Lymphoma

Cancer Investigation, 2007
A 33-year-old male presented with a complaint of intermittently blurred vision and right facial weakness. MRI of the brain and orbits revealed numerous cranial nerve abnormalities. There were no focal brain or spinal cord lesions. Cerebral spinal fluid flow cytometry revealed a monoclonal population of B-lymphoid cells. No other evidence of disease was
Huzefa, Bahrain, Robert, Laureno, Jayshree, Krishnan, Anita, Aggarwal, Vera, Malkovska   +4 more
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Applications of carbonic anhydrases inhibitors in renal and central nervous system diseases

Expert Opinion on Therapeutic Patents, 2018
Introduction: There are tissues and organs, among which kidneys and the central nervous system (CNS), rich in various isoforms of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1).
C. Supuran
semanticscholar   +1 more source

Central Nervous System Imaging in Rheumatic Diseases

Rheumatic Disease Clinics of North America
Central nervous system (CNS) involvement is seen across a variety of rheumatic diseases. Common CNS manifestations include cerebrovascular events (such as ischemic and hemorrhagic strokes, cerebral venous sinus thrombosis), seizures, headaches, demyelinating lesions (such as optic neuritis, myelitis, parenchymal lesions), meningeal disease ...
Shervin, Badihian, Matthew P, Kiczek, Rula A, Hajj-Ali   +2 more
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Central Nervous System Whipple Disease

2017
Whipple disease (WD) is a multisystemic infection caused by the bacillus Tropheryma whipplei. Although the organism is ubiquitous in the environment, WD is rare. In affected individuals, the organism resides intracellularly within macrophages and can manipulate host immune responses to avoid clearance. Central nervous system (CNS) involvement can occur
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Parasitic diseases of the central nervous system

Seminars in Diagnostic Pathology, 2010
Parasitic infections, though endemic to certain regions, have over time appeared in places far removed from their original sites of occurrence facilitated probably by the increase in world travel and the increasing migration of people from their native lands to other, often distant, countries.
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