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Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
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HLA-transgenic mouse models to study autoimmune central nervous system diseases. [PDF]
Pressley KR +5 more
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Label‐Free SERS Fingerprinting of Neuroprotein Conformational Dynamics in Human Saliva
Galvanic molecular entrapment (GME) is a label‐free method for detecting and quantifying neuroprotein conformational states. This technique enables direct surface binding and in situ hotspot generation around molecules, effectively overcoming challenges related to target localization and mismatched hotspot geometries.
Muhammad Shalahuddin Al Ja'farawy +10 more
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Exosomes in Central Nervous System Diseases: A Comprehensive Review of Emerging Research and Clinical Frontiers. [PDF]
Li J +6 more
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Extracellular vesicles as drug and gene delivery vehicles in central nervous system diseases.
Shi X +10 more
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Ergothioneine and central nervous system diseases
Neurochemical Research, 2022Ergothioneine (ERGO) is a thiol contained in the food that exhibits an excellent antioxidant effect similar to that of glutathione. Although mammals lack a biosynthetic pathway for ERGO, the carnitine/organic cation transporter OCTN1/SLC22A4, which transports ERGO in vivo, is expressed throughout the body, and ERGO is distributed to various organs ...
N. Nakamichi +2 more
semanticscholar +3 more sources
The glymphatic system: implications for drugs for central nervous system diseases
Nature Reviews Drug Discovery, 2022T. Lohela +2 more
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Ageing Research Reviews, 2023
Central nervous system (CNS) diseases have become one of the leading causes of death in the global population. The pathogenesis of CNS diseases is complicated, so it is important to find the patterns of the disease to improve the treatment strategy ...
Yu Long +15 more
semanticscholar +1 more source
Central nervous system (CNS) diseases have become one of the leading causes of death in the global population. The pathogenesis of CNS diseases is complicated, so it is important to find the patterns of the disease to improve the treatment strategy ...
Yu Long +15 more
semanticscholar +1 more source

