Results 261 to 270 of about 1,580,164 (331)

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

HLA-transgenic mouse models to study autoimmune central nervous system diseases. [PDF]

open access: yesAutoimmunity
Pressley KR   +5 more
europepmc   +1 more source

Label‐Free SERS Fingerprinting of Neuroprotein Conformational Dynamics in Human Saliva

open access: yesAdvanced Materials, EarlyView.
Galvanic molecular entrapment (GME) is a label‐free method for detecting and quantifying neuroprotein conformational states. This technique enables direct surface binding and in situ hotspot generation around molecules, effectively overcoming challenges related to target localization and mismatched hotspot geometries.
Muhammad Shalahuddin Al Ja'farawy   +10 more
wiley   +1 more source

Extracellular vesicles as drug and gene delivery vehicles in central nervous system diseases.

open access: yesBiomater Sci
Shi X   +10 more
europepmc   +1 more source
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Ergothioneine and central nervous system diseases

Neurochemical Research, 2022
Ergothioneine (ERGO) is a thiol contained in the food that exhibits an excellent antioxidant effect similar to that of glutathione. Although mammals lack a biosynthetic pathway for ERGO, the carnitine/organic cation transporter OCTN1/SLC22A4, which transports ERGO in vivo, is expressed throughout the body, and ERGO is distributed to various organs ...
N. Nakamichi   +2 more
semanticscholar   +3 more sources

The glymphatic system: implications for drugs for central nervous system diseases

Nature Reviews Drug Discovery, 2022
T. Lohela   +2 more
semanticscholar   +3 more sources

Modulating the polarization phenotype of microglia - a valuable strategy for central nervous system diseases.

Ageing Research Reviews, 2023
Central nervous system (CNS) diseases have become one of the leading causes of death in the global population. The pathogenesis of CNS diseases is complicated, so it is important to find the patterns of the disease to improve the treatment strategy ...
Yu Long   +15 more
semanticscholar   +1 more source

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