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Extracellular vesicles as drug and gene delivery vehicles in central nervous system diseases.
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Parasitic Diseases of the Central Nervous System
Neuroimaging Clinics of North America, 2011This article reviews the characteristic imaging appearances of parasitic diseases of the central nervous system, including cysticercosis, toxoplasmosis, cystic echinococcosis, schistosomiasis, amebiasis, malariasis, sparganosis, paragonimiasis, and American and African trypanosomiases.
Ahmed Abdel Khalek Abdel Razek +2 more
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The glymphatic system: implications for drugs for central nervous system diseases
Nature Reviews Drug Discovery, 2022 In the past decade, evidence for a fluid clearance pathway in the central nervous system known as the glymphatic system has grown. According to the glymphatic system concept, cerebrospinal fluid flows directionally through the brain and non-selectively ...
Terhi J Lohela +2 more
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Batokine in Central Nervous System Diseases
Molecular Neurobiology, 2023Brown adipose tissue (BAT) is a special type of fat tissue in mammals and is also a key endocrine organ in the human body. Batokine, the endocrine effector of BAT, plays a neuroprotective role and improves the prognosis by exerting anti-apoptotic and anti-inflammatory effects, as well as by improving vascular endothelial function and other mechanisms ...
Ming Shen +3 more
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Inflammatory Diseases of the Central Nervous System
Neurologic Clinics, 2021Pediatric neuroinflammatory conditions are a complex group of disorders with a wide range of clinical presentations. Patients can present with a combination of focal neurologic deficits, encephalopathy, seizures, movement disorders, or psychiatric manifestations.
Nikita, Malani Shukla +2 more
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Ergothioneine and central nervous system diseases
Neurochemical Research, 2022Ergothioneine (ERGO) is a thiol contained in the food that exhibits an excellent antioxidant effect similar to that of glutathione. Although mammals lack a biosynthetic pathway for ERGO, the carnitine/organic cation transporter OCTN1/SLC22A4, which transports ERGO in vivo, is expressed throughout the body, and ERGO is distributed to various organs ...
Noritaka Nakamichi +2 more
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Amyloid in central nervous system disease
Clinical Neurology and Neurosurgery, 1990A review is presented of diseases of the central nervous system associated with amyloid deposition. The name amyloid is given to substances with particular physical characteristics which are independent of the chemical constitution of the proteins in the substance.
J, Haan, R A, Roos
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Central nervous system Lyme disease
Seminars in Pediatric Infectious Diseases, 2003Lyme disease is a disease caused by the spirochete, Borrelia burgdorferi. It is transmitted to humans via a bite from an infected tick. It has several classic stages or categories of illness, including early localized disease, early disseminated disease, and late disease.
Sharon A, Nachman, Lucy, Pontrelli
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Granulomatous Diseases of the Central Nervous System
Current Neurology and Neuroscience Reports, 2022To discuss the pathophysiology, key clinical features, necessary diagnostic evaluation, and current treatment regimens for granulomatous diseases of the central nervous system.The diagnosis and management of granulomatous disease of the central nervous system has been revolutionized by advances in diagnostic imaging.
Braden, Dasovic +2 more
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Transglutaminase and diseases of the central nervous system
Frontiers in Bioscience, 2005Alzheimer's disease, Parkinson's disease and diseases of expanded polyglutamine are associated with insoluble protein aggregates and neuronal death. A role for transglutaminase in the stabilization of these aggregates has been proposed. Diseases of polyglutamine expansion have been the most thoroughly investigated and a large body of studies supports ...
Hoffner, Guylaine, Djian, Philippe
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