Results 231 to 240 of about 24,516,016 (295)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Targeting Neuroinflammation in Central Nervous System Diseases by Oral Delivery of Lipid Nanoparticles. [PDF]

Pharmaceutics
Zou Y, Zhang J, Chen L, Xu Q, Yao S, Chen H.   +5 more
europepmc   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

The microbiota-gut-brain axis and central nervous system diseases: from mechanisms of pathogenesis to therapeutic strategies. [PDF]

Front Microbiol
Xu J, Lu Y.
europepmc   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Research progress on the role of ginsenoside Rd in central nervous system diseases. [PDF]

Afr Health Sci
Ma X, Wang J.
europepmc   +1 more source

Characteristics of Parthenogenetic Stem Cells and Their Potential Treatment Strategy for Central Nervous System Diseases. [PDF]

Neuropsychiatr Dis Treat
Cai H, Huang J, Wang W, Lin W, Ahmed W, Lu D, Quan J, Chen L.   +7 more
europepmc   +1 more source

Intranasal Drug Delivery Technology in the Treatment of Central Nervous System Diseases: Challenges, Advances, and Future Research Directions. [PDF]

Pharmaceutics
Wu X, Zang R, Qiu Y, Zhang Y, Peng J, Cheng Z, Wei S, Liu M, Diao Y.   +8 more
europepmc   +1 more source

Meningeal Lymphatics in Central Nervous System Diseases. [PDF]

Annu Rev Neurosci
Salvador AFM, Abduljawad N, Kipnis J.
europepmc   +1 more source

Infections of the central nervous system

, 2004
Scheld, W. Michael, Marra, Christina M., Whitley, Richard J.   +2 more
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