Results 101 to 110 of about 8,000,685 (282)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Variability in neural networks
eLife, 2018 Experiments on neurons in the heart system of the leech reveal why rhythmic behaviors differ between individuals.
Daniel R Kick, David J Schulz
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Central's first homecoming; male students standing on street in single file line
, 1920 In Central Methodist University (formerly Central College)'s first homecoming parade, male students in costume stand in single file on an unpaved road in Fayette ...
Central Methodist University, Smiley Memorial Library
core +1 more source
A Single Central Pattern Generator for the Control of a Locomotor Rolling Wave in Mollusc Aplysia. [PDF]
Research (Wash D C), 2023 Wang HY +16 more
europepmc +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Analisi e sintesi di Central Pattern Generator
, 2019 Negli esseri viventi, un Central Pattern Generator (CPG) è una rete di neuroni relativamente piccola, in grado di produrre pattern ritmici anche in assenza di feedback sensoriali o di segnali provenienti dal sistema nervoso centrale.
LODI, MATTEO
core +1 more source
Central Pattern Generator with Defined Pulse Signals for Compliant-Resistant Control of Biped Robots. [PDF]
Biomimetics (Basel), 2023 Xu Z, Fang Q, Liu C, Chen Q.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source