Results 81 to 90 of about 8,000,685 (282)

Classification of rhythmic locomotor patterns in electromyographic signals using fuzzy sets

open access: yesJournal of NeuroEngineering and Rehabilitation, 2011
Background Locomotor control is accomplished by a complex integration of neural mechanisms including a central pattern generator, spinal reflexes and supraspinal control centres.
Thrasher Timothy A   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Respiratory rhythm generation: A modeling study of the respiratory central pattern generator and the phrenic motor neuron

open access: yes, 2005
The respiratory central pattern generator is a collection of medullary neurons that generates the rhythm of respiration. The respiratory central pattern generator feeds phrenic motor neurons, which, in turn, drive the main muscle of respiration, the ...
Amini, Behrang
core   +1 more source

The ins and outs of breathing

open access: yeseLife, 2014
Distinct populations of neurons within the brainstem are responsible for generating and coordinating the rhythmic patterns of neural activity that underlie breathing.
Jan-Marino Ramirez   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

General Principles of Rhythmogenesis in Central Pattern Generator Networks [PDF]

open access: yes, 2010
The cellular and ionic mechanisms that generate the rhythm in central pattern generator (CPG) networks for simple movements are not well understood. Using vertebrate locomotion, respiration and mastication as exemplars, I describe four main principles of rhythmogenesis: (1) rhythmogenic ionic currents underlie all CPG networks, regardless of whether ...
openaire   +2 more sources

Adaptive-Frequency Central Pattern Generator with Multi-Scale Feedback for Dynamic Quadruped Locomotion

open access: yesActuators
This paper studies a MuJoCo-based locomotion framework that couples an adaptive-frequency central pattern generator (AFCO-CPG) with single rigid-body dynamics model predictive control (MPC) for the RENS Q1 quadruped with elastic parallel knee joints ...
Rui Qin   +3 more
doaj   +1 more source

Dopamine: A parallel pathway for modulation of locomotor networks

open access: yesFrontiers in Neural Circuits, 2014
The spinal cord contains networks of neurons that can produce locomotor patterns. To readily respond to environmental conditions, these networks must be flexible yet at the same time robust.
Simon eSharples   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Hintergrund: Central Pattern Generator – Hypothesen und Evidenz

open access: yes, 2010
Die Fortbewegung des Menschen basiert auf der Aktivität neuronaler Schaltkreise im Rückenmark, dem Central Pattern Generator (CPG). Afferente Informationen von der Peripherie, also den Extremitäten, beeinflussen diesen.
Dietz, V
core   +1 more source

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