Results 71 to 80 of about 36,645 (254)

Dopamine: A parallel pathway for modulation of locomotor networks

Frontiers in Neural Circuits, 2014
The spinal cord contains networks of neurons that can produce locomotor patterns. To readily respond to environmental conditions, these networks must be flexible yet at the same time robust.
Simon eSharples, Kathrin eKoblinger, Jennifer eHumphreys, Patrick John Whelan   +3 more
doaj   +1 more source

Animal‐Assisted Activities With Therapy Dogs in Pediatric Oncology: A Multicenter Survey of the Current Status, Implementation, and Challenges in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig, Birgit Burkhardt, Christof M. Kramm, Kira Ostermann, Sarah C. Goretzki, Uta Dirksen, Nico Kurpiers, Michael M. Schündeln   +7 more
wiley   +1 more source

General Principles of Rhythmogenesis in Central Pattern Generator Networks [PDF]

, 2010
The cellular and ionic mechanisms that generate the rhythm in central pattern generator (CPG) networks for simple movements are not well understood. Using vertebrate locomotion, respiration and mastication as exemplars, I describe four main principles of rhythmogenesis: (1) rhythmogenic ionic currents underlie all CPG networks, regardless of whether ...
openaire   +2 more sources

Benchmarking Open-Loop Central Pattern Generator Controllers for Lower-Limb Exoskeleton Walking Trajectories

IEEE Access
Central Pattern Generators (CPGs) enable rhythmic, biologically inspired control of robotic locomotion. This study presents a comparative evaluation of three CPG models: Hopf, Matsuoka, and sinusoidal implemented on a simplified lower-limb exoskeleton ...
Hod Pery, Tal Ben Eli, Eldad Holdengreber   +2 more
doaj   +1 more source

Atoh1-dependent rhombic lip neurons are required for temporal delay between independent respiratory oscillators in embryonic mice

eLife, 2014
All motor behaviors require precise temporal coordination of different muscle groups. Breathing, for example, involves the sequential activation of numerous muscles hypothesized to be driven by a primary respiratory oscillator, the preBötzinger Complex ...
Srinivasan Tupal, Wei-Hsiang Huang, Maria Cristina D Picardo, Guang-Yi Ling, Christopher A Del Negro, Huda Y Zoghbi, Paul A Gray   +6 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

A Single Central Pattern Generator for the Control of a Locomotor Rolling Wave in Mollusc Aplysia. [PDF]

Research (Wash D C), 2023
Wang HY, Yu K, Yang Z, Zhang G, Guo SQ, Wang T, Liu DD, Jia RN, Zheng YT, Su YN, Lou Y, Weiss KR, Zhou HB, Liu F, Cropper EC, Yu Q, Jing J.   +16 more
europepmc   +1 more source

Bionic Walking Control of a Biped Robot Based on CPG Using an Improved Particle Swarm Algorithm

Actuators
In the domain of bionic walking control for biped robots, optimizing the parameters of the central pattern generator (CPG) presents a formidable challenge due to its high-dimensional and nonlinear characteristics.
Yao Wu, Biao Tang, Shuo Qiao, Xiaobing Pang   +3 more
doaj   +1 more source