Results 91 to 100 of about 6,129,726 (293)
[Therapy of disorders with central pain sensitization.]
Previous somatic pain experience (priming), psychobiographic imprinting (pain proneness), and stress (action proneness) are key to an enhanced centralised pain response. This centralised pain response clinically manifests itself in pain sensitization and
Egloff, N, Egle, U T, von Känel, R
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Central's first homecoming; male students standing on street in single file line
In Central Methodist University (formerly Central College)'s first homecoming parade, male students in costume stand in single file on an unpaved road in Fayette ...
Central Methodist University, Smiley Memorial Library
core +1 more source
Background and Objectives: Low back pain (LBP) is highly prevalent and often associated with altered muscle function, including in the quadratus lumborum (QL) muscle.
Mónica López-Redondo +7 more
doaj +1 more source
Using pixel‐aware digital light processing, the authors created high‐resolution, dissolvable microneedles from a PEGDA/VP matrix. These microneedles encapsulate curcumin and 5‐fluorouracil and dissolve in the skin, co‐delivering drugs directly to tumours.
Rutuja N. Meshram, Dimitrios A. Lamprou
wiley +1 more source
The Thermal Grill Elicits Central Sensitization
Abstract The thermal grill, in which innocuous warm and cool stimuli are interlaced, can produce a paradoxical burning pain sensation—the thermal grill illusion (TGI). While the mechanisms underlying TGI remain unclear, prominent theories point to spinal dorsal horn integration of innocuous thermal inputs to elicit pain.
Matthew Alexander Cormie +2 more
openaire +2 more sources
CHRONIC BACK PAIN: FROM PATHOGENETIC CONCEPTS TO THERAPEUTIC STRATEGIES
Social losses and expenses of healthcare resources related to chronic back pain continue remaining a high burden for the society. The mechanism of the central sensitization partially accounts for the formation of the chronic back pain, but these ...
O. V. Vorobieva
doaj +1 more source
Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull +11 more
wiley +1 more source
Ping Zheng*, Wen Zhang*, Jinhua Leng, Jinghe LangDepartment of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, People’s Republic of China*These authors ...
Zhang W, Lang J, Zheng P, Leng J
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Beibei Feng,1– 4,* Chen Gong,1,3,4,* Longfei You,1,3,4,* Yangyang Lin,1,3,4 Yafei Wang,1,3,4 Wing Yuk Ip,2 Yuling Wang1,3,4 1Department of Rehabilitation Medicine, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s ...
You L +5 more
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