Results 101 to 110 of about 726,644 (313)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Residential and support services for older people in the Waikato, 1992-1997: Privatisation and emerging resistance [PDF]

open access: yes, 1999
As disproportionate users of services, older people are more vulnerable to shifts in policy in health care and social support. This paper focuses on older people as a group affected by economic and social restructuring.
Chalmers, Lex, Joseph, Alun E.
core   +1 more source

Lessons learned during down referral of antiretroviral treatment in Tete, Mozambique. [PDF]

open access: yes, 2009
: As sub-Saharan African countries continue to scale up antiretroviral treatment, there has been an increasing emphasis on moving provision of services from hospital level to the primary health care clinic level.
Tom Decroo   +13 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Genome of a novel Fangshan bunya-like virus identified in mosquitoes from Shandong Province, China

open access: yesScientific Reports
Mosquitoes are important vectors of a wide range of viruses and serve as pivotal vectors with complex ecological functions that facilitate the transmission of these pathogens between hosts, such as humans, through biting behavior.
Yuli Zhang   +7 more
doaj   +1 more source

Variations and trends in state nursing facility capacity: 1978-93. [PDF]

open access: yes, 1995
The demand for nursing facility (NF) beds has been growing with the aging of the population and many other factors. As the need for nursing home care grows, the Nation's capacity to provide such care is the subject of increasing concern.
Bedney, B   +3 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A qualitative analysis on the awareness of noise pollution and occupational protection among staff members of the Central Sterile Supply Department (消毒供应中心工作人员对噪声污染的认知及职业防护质性分析)

open access: yes中西医结合护理
Objective To understand the awareness of noise pollution among the staff in the Central Sterile Supply Department, as well as the usage of protective measures, and to provide a basis for reducing the environmental noise in the Central Sterile Supply ...
HUANG Xuanxuan (黄玄玄)   +5 more
doaj   +1 more source

216 Jewish Hospital of St. Louis [PDF]

open access: yes, 1960
https://digitalcommons.wustl.edu/bjc_216/1045/thumbnail ...

core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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