Results 71 to 80 of about 8,628 (221)

Chapter 31 Central Immune Senescence, Reversal Potentials [PDF]

open access: yes, 2012
Ageing is a complex process that affects all living organisms. Senescence is not only conceivable in multicellular organisms, but also in unicellulars. Unlike certain diseases that have specific morbidity rates, ageing is a physiological process that affects all individuals that live long enough (unaffected by i.e.
Kvell, Krisztian, Pongracz, Judit E.
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Territorio, Tecnología y Capital : la regulación hidroeléctrica de los ríos españoles (1900-1970) [PDF]

open access: yes, 2008
Aquest article presenta una anàlisi sobre les relacions històriques i actuals entre el capital, l'obra civil, els regadius i l'energia hidroelèctrica en el procés de regulació hidrològica a Espanya.
Arroyo Ilera, Fernando
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

[National recommendations on pediatric donation]. [PDF]

open access: yesAn Pediatr (Engl Ed), 2020
Rodríguez Núñez A   +4 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Diàleg transfronterer en una cruïlla pirinenca. Coincidències lexicas d'Aran i Comenge [PDF]

open access: yes, 2006
La Vall d'Aran està separada de la resta del domini occità per una línia administrativa que talla perpendicularment la conca de la Garona, l'única sortida de la comarca sense grans obstacles físics.
Carrera Baiget, Aitor
core  

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Alteraciones neuropsicológicas en el alcoholismo crónico [PDF]

open access: yes, 2016
El déficit neuropsicológico asociado al alcholismo abarca diversas funciones: memoria, razonamiento abstracto, solución de problemas y ha- bilidades perceptivo-motoras.
Junqué i Plaja, Carme, 1955-   +1 more
core  

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