Results 71 to 80 of about 8,976 (287)

Substance and chemical reaction as core concepts in chemistry. A conceptual, historical and pedagogical discussion [PDF]

open access: yes, 2011
En este articulo se lleva a cabo una discusion conceptual, historica y didactica de dos conceptos centrales de la quimica: sustancia y reaccion quimica, en sus aspectos macroscopico y nanoscopico.
Garritz, Andoni   +2 more
core   +2 more sources

0992 Reversible Pediatric Central Sleep Apnea in Hyperhomocysteinemia and Cerebral Sinus Venous Thrombosis [PDF]

open access: bronze, 2023
Kevin Coughlin   +4 more
openalex   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Chapter 31 Central Immune Senescence, Reversal Potentials [PDF]

open access: yes, 2012
Ageing is a complex process that affects all living organisms. Senescence is not only conceivable in multicellular organisms, but also in unicellulars. Unlike certain diseases that have specific morbidity rates, ageing is a physiological process that affects all individuals that live long enough (unaffected by i.e.
Kvell, Krisztian, Pongracz, Judit E.
openaire   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Diàleg transfronterer en una cruïlla pirinenca. Coincidències lexicas d'Aran i Comenge [PDF]

open access: yes, 2006
La Vall d'Aran està separada de la resta del domini occità per una línia administrativa que talla perpendicularment la conca de la Garona, l'única sortida de la comarca sense grans obstacles físics.
Carrera Baiget, Aitor
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

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