Results 91 to 100 of about 4,379,473 (311)
Services informatiques et centralités métropolitaines en région parisienne
The diffusion of software services reveals new centralities inside a complicated metropolitan area. Classic evolutions toward polycentrality and high territory contrasts are increasing.
Jacques Fache
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Identification of top-K nodes in large networks using Katz centrality
Network theory concepts form the core of algorithms that are designed to uncover valuable insights from various datasets. Especially, network centrality measures such as Eigenvector centrality, Katz centrality, PageRank centrality etc., are used in ...
J. Zhan +2 more
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
An important task in trajectory analysis is clustering. The results of a clustering are often summarized by a single representative trajectory and an associated size of each cluster. We study the problem of computing a suitable representative of a set of similar trajectories.
van Kreveld, M.J. +2 more
openaire +4 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Port Competition and Network Polarization in the East Asian Maritime Corridor
Port competition is often analyzed based on individual characteristics of seaports rather than inter-port connections. A maritime network perspective is applied to the circulation of liner vessels between East Asian ports in order to reveal their ...
César Ducruet +2 more
doaj +1 more source
The Centrality of Religiosity Scale (CRS)
The Centrality of Religiosity Scale (CRS) is a measure of the centrality, importance or salience of religious meanings in personality that has been applied yet in more than 100 studies in sociology of religion, psychology of religion and religious ...
Stefan Huber, Odilo W. Huber
semanticscholar +1 more source
The Influence of Closeness Centrality on Lexical Processing
The present study examined how the network science measure known as closeness centrality (which measures the average distance between a node and all other nodes in the network) influences lexical processing.
Rutherford Goldstein, M. Vitevitch
semanticscholar +1 more source

