Results 101 to 110 of about 519,794 (298)
Services informatiques et centralités métropolitaines en région parisienne
Belgeo, 2003 The diffusion of software services reveals new centralities inside a complicated metropolitan area. Classic evolutions toward polycentrality and high territory contrasts are increasing.
Jacques Fache
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A Faster Method to Estimate Closeness Centrality Ranking [PDF]
, 2017 Closeness centrality is one way of measuring how central a node is in the given network. The closeness centrality measure assigns a centrality value to each node based on its accessibility to the whole network.
Gera, Ralucca +2 more
core +1 more source
Journal of Computational Geometry, 2015 An important task in trajectory analysis is clustering. The results of a clustering are often summarized by a single representative trajectory and an associated size of each cluster. We study the problem of computing a suitable representative of a set of similar trajectories.
van Kreveld, M.J. +2 more
openaire +4 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A Content-based Centrality Metric for Collaborative Caching in Information-Centric Fogs [PDF]
, 2017 Information-Centric Fog Computing enables a multitude of nodes near the end-users to provide storage, communication, and computing, rather than in the cloud.
Ghamri-Doudane, Yacine +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Semantic Network Analysis of Ontologies [PDF]
, 2011 A key argument for modeling knowledge in ontologies is the easy re-use and re-engineering of the knowledge. However, current ontology engineering tools provide only basic functionalities for analyzing ontologies.
Hoser, Bettina +4 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Port Competition and Network Polarization in the East Asian Maritime Corridor
Territoire en Mouvement, 2011 Port competition is often analyzed based on individual characteristics of seaports rather than inter-port connections. A maritime network perspective is applied to the circulation of liner vessels between East Asian ports in order to reveal their ...
César Ducruet +2 more
doaj +1 more source