Results 121 to 130 of about 169,804 (304)
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
We study a recently developed centrality metric to identify key players in terrorist organisations due to Lindelauf et al. [2013]. This metric, which involves computation of the Shapley value for connectivity games on graphs proposed by Amer and Gimenez [
Rahwan, Talal +6 more
core +1 more source
This research uses social network connections and academic data to create a recommender system that helps students choose seminars and events that suit their interests. The aim is to address the issue of students' hesitation in selecting activities. This
Esther Setiawan +7 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The dynamics of closeness and betweenness [PDF]
Although both betweenness and closeness centrality are claimed to be important for the effectiveness of someones network position, it has not been explicitly studied which networks emerge if actors follow incentives for these two positional advantages ...
Vincent Buskens, Berno Buechel
core
This study applies a graph-theoretic framework to analyze the structural dynamics of codon networks derived from SARS-CoV-2 spike protein sequences. By employing a dual-level analysis of Minimum Connected Dominating Sets (MCDS) and community structures,
L. Praveenkumar +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Nestedness in Networks: A Theoretical Model and Some Applications [PDF]
We develop a dynamic network formation model that can explain the observed nestedness in real-world networks. Links are formed on the basis of agents’ centrality and have an exponentially distributed life time. We use stochastic stability to identify the
Yves Zenou +2 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Network Centrality in the Human Functional Connectome
The network architecture of functional connectivity within the human brain connectome is poorly understood at the voxel level. Here, using resting state functional magnetic resonance imaging data from 1003 healthy adults, we investigate a broad array of ...
Castellanos, F. Xavier +7 more
core

