Economies of signs in writing for academic publication: the case of English Medium “National” Journals [PDF]
The centrality of publishing in academic journals to academic knowledge work globally is largely taken as a given. Publishing is a defining aspect of scholars’ labour in the academic world, tied to both current and possible future material conditions in ...
Lillis, Theresa
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Analysis and Overall Evaluation of Latin American Trade Policies [PDF]
Development thlnking and practive in Latin America have been strongly influenced by the centre-periphery approach with its heavy emphasis on international trade, considered the most important variable in the analytical explanation of the origin of ...
Sideri, S. (Sandro)
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
An Interdyscyplinary Model of Centre-Periphery Relations: A Theoretical Proposition
The paper proposes a model in which centre-periphery relations defined at a high level of generality (from the global level down to regional structures) can be analysed from a perspective of a number of disciplines, including political science (e.g ...
Tomasz Zarycki
doaj
Environmental Justice in the European Union: A Critical Reassessment
The paper discusses the concept of ‘environmental justice’ in the European Union, approaching it from the perspective of the centre-periphery gap in the EU, that is, the divide between the Member States from Western and Northern Europe on the one hand ...
Davor Petrić
doaj +1 more source
An Account of Geographic Concentration Patterns in Europe [PDF]
Using entropy indices and associated bootstrap tests, we describe the distribution of economic sectors across Western European regions over the 1975-2000 period.
Brülhart, Marius, Traeger, Rolf
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Regional Cleavage Influence towards Island Electoral Behavior: evidences from the Canaries [PDF]
The Canary Islands are a region with legislative capacities within the European Union (EU). It has had always serious socio-economic deficits.
Tuñón, Jorge
core +1 more source

