Results 61 to 70 of about 81,839 (258)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Esilio, ibridazione, nazionalismo. L’esperienza poetica di Yahya Kemal e Nazım Hikmet

Lea, 2013
This essay examines the relationship between the centre and the periphery in the context of the construction of a literary and national subject within the development of Turkish literature of the late 19th and early 20th centuries. Focusing on the figure
Ayşe Saraçgil
doaj   +1 more source

When ecological marginality is not geographically peripheral: exploring genetic predictions of the centre-periphery hypothesis in the endemic plant Lilium pomponium. [PDF]

PeerJ, 2021
Casazza G, Macrì C, Dagnino D, Guerrina M, Juin M, Minuto L, Thompson JD, Baumel A, Médail F.   +8 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The strategies of Decentralization and Hybridization in Nadine Gordimer`s July`s people

آداب الكوفة
             The dichotomy of centre vs periphery is a central idea in postcolonial theory and an important model to describe the relationship between colonizer and colonized.
امير حسين, قاسم سرحان
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Critique and System: Early and Late Natorp’s Philosophy

RUDN Journal of Philosophy
This paper presents an interpretation of the connection between Natorp’s early and late philosophy. An analysis of two versions of Natorp’s deduction of categories shows the consistent development of Natorp’s thought.
Hernán Pringe
doaj   +1 more source

Pour un modèle centre-périphérie dans les sciences sociales

Revue d'anthropologie des connaissances, 2010
This paper deals with global hierarchies and inequalities in the production and diffusion of sociological knowledge in a North-South perspective. A centre-periphery-model is proposed in order to apprehend these inequalities.
Wiebke Keim
doaj   +1 more source